#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4420660	B	Inhibition of human LATS1 kinase domain (589 to 1130 amino acids) incubated for 30 mins by HTRF assay	Homo sapiens	244		single protein format	Patent Bioactivity Data
2.	ALA4420662	B	Inhibition of human LATS2 kinase domain (553 to 1088 amino acids) incubated for 3 hrs in presence of FAM-KKLRRTLSVA-COOH by fluorescence detection based biochemical caliper assay	Homo sapiens	244		single protein format	Patent Bioactivity Data
3.	ALA4420664	B	Inhibition of LATS in human HaCaT cells assessed as reduction in YAP phosphorylation level incubated for 2 hrs by HTRF assay	Homo sapiens	244		cell-based format	Patent Bioactivity Data
4.	ALA4420665	B	Inhibition of LATS in human HaCaT cells assessed as reduction in YAP nuclear translocation incubated for 24 hrs	Homo sapiens	244		cell-based format	Patent Bioactivity Data
5.	ALA4420671	B	Inhibition of LATS in human JHH5 cells assessed as reduction in YAP phosphorylation level incubated for 2 hrs by HTRF assay	Homo sapiens	284		cell-based format	Patent Bioactivity Data
6.	ALA4420673	F	Inhibition of LATS in C57BL/6J mouse assessed as YAP phosphorylation level in liver at 10 mg/kg, po administered as single dose measured after 24 hrs by HTRF assay	Mus musculus	1		organism-based format	Patent Bioactivity Data
7.	ALA4420675	F	Inhibition of LATS in C57BL/6J mouse assessed as change in CTGF mRNA expression level at 10 mg/kg, po administered as single dose measured after 2 hrs by qRT-PCR analysis relative to control	Mus musculus	1		organism-based format	Patent Bioactivity Data
8.	ALA4420677	F	Inhibition of LATS in C57BL/6J mouse assessed as change in Cyr61 mRNA expression level at 10 mg/kg, po administered as single dose measured after 2 hrs by qRT-PCR analysis relative to control	Mus musculus	1		organism-based format	Patent Bioactivity Data
9.	ALA4420679	F	Inhibition of LATS in C57BL/6J mouse assessed as change in Ki67 protein expression level at 10 mg/kg, po administered as single dose measured after 24 hrs by immunohistochemistry analysis relative to control	Mus musculus	1		organism-based format	Patent Bioactivity Data
10.	ALA4420683	B	Inhibition of LATS in human limbal epithelial cells assessed as induction of limbal stem cell expansion by measuring expansion factor ratio at 10 uM measured after 2 weeks by p63alpha expression detection based immunohistochemistry relative to control	Homo sapiens	18		cell-based format	Patent Bioactivity Data
11.	ALA4420684	B	Inhibition of LATS in human limbal epithelial cells assessed as induction of limbal stem cell expansion by measuring measuring ratio of expanded population of cells to population of seeded cells at 10 uM measured after 2 weeks by p63alpha expression detection based immunohistochemistry	Homo sapiens	18		cell-based format	Patent Bioactivity Data
12.	ALA4420685	B	Inhibition of LATS in human limbal epithelial cells assessed as induction of limbal stem cell expansion by measuring p63alpha expression at 10 uM measured after 2 weeks by immunohistochemistry relative to control	Homo sapiens	18		cell-based format	Patent Bioactivity Data
13.	ALA4420689	B	Inhibition of LATS in human limbal epithelial cells assessed as induction of cell differentiation into corneal epithelial cells by measuring keratin-12 expression at 10 uM incubated for 8 to 10 days followed by medium change to DMEM medium without serum and compound for further incubation for 4 to 8 days by confocal microscopy	Homo sapiens	4		cell-based format	Patent Bioactivity Data
14.	ALA4420693	A	Total drug level in cell pellets of human limbal stem cells by LC-MS analysis	Homo sapiens	4		assay format	Patent Bioactivity Data
15.	ALA4420694	A	Drug level in post wash cell pellets of human limbal stem cells by LC-MS analysis	Homo sapiens	4		assay format	Patent Bioactivity Data
16.	ALA4420698	B	Inhibition of LATS in human corneal endothelium cells assessed as induction of cell expansion by measuring ratio of expanded population of cells to population of seeded cells at 10 uM by Sytox orange dye based epifluorescence microscopy	Homo sapiens	21		assay format	Patent Bioactivity Data
17.	ALA4420699	B	Inhibition of LATS in human corneal endothelium cells assessed as induction of cell expansion by measuring cell density at 10 uM by Sytox orange dye based epifluorescence microscopy	Homo sapiens	21		assay format	Patent Bioactivity Data