# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4370851 | B | Inhibition of recombinant His-tagged human cathepsin K expressed in Escherichia coli | Homo sapiens | 2 | ALA4368938 | assay format | Scientific Literature | |
2. | ALA4370852 | B | Inhibition of human liver cathepsin L | Homo sapiens | 2 | ALA4368938 | assay format | Scientific Literature | |
3. | ALA4370853 | B | Inhibition of recombinant human cathepsin S expressed in Escherichia coli | Homo sapiens | 2 | ALA4368938 | assay format | Scientific Literature | |
4. | ALA4370854 | B | Inhibition of human liver cathepsin B | Homo sapiens | 2 | ALA4368938 | assay format | Scientific Literature | |
5. | ALA4370855 | A | Cytotoxicity against human MG63 cells assessed as reduction in cell viability at 0.001 to 5 uM after 3 days by MTT assay | Homo sapiens | 2 | ALA4368938 | cell-based format | Scientific Literature | |
6. | ALA4370856 | A | Cytotoxicity against mouse MOVAS1 cells assessed as reduction in cell viability at 0.001 to 5 uM after 3 days by MTT assay | Mus musculus | 2 | ALA4368938 | cell-based format | Scientific Literature | |
7. | ALA4370857 | A | Cytotoxicity against mouse Primary chondrocytes assessed as reduction in cell viability at 0.001 to 5 uM after 3 days by MTT assay | Mus musculus | 2 | ALA4368938 | assay format | Scientific Literature | |
8. | ALA4370858 | B | Inhibition of cathepsin K in mouse Primary chondrocytes derived after 2 passages at 0.1 to 1 uM using Z-GPR-4MbetaNA as substrate by fluorescence assay relative to control | Mus musculus | 3 | ALA4368938 | cell-based format | Scientific Literature | |
9. | ALA4370859 | B | Inhibition of aggrecanase in mouse Primary chondrocytes derived after 1 passages assessed as effect on measuring sGAG content at 1 uM by Alcian blue staining-based assay | Mus musculus | 2 | ALA4368938 | cell-based format | Scientific Literature | |
10. | ALA4370860 | B | Inhibition of cathepsin K in mouse Primary chondrocytes derived after 2 passages at 1 uM after 24 hrs by Coomassie blue staining-based zymography assay | Mus musculus | 3 | ALA4368938 | cell-based format | Scientific Literature | |
11. | ALA4370861 | B | Inhibition of aggrecanase in mouse Primary chondrocytes derived after 2 passages assessed as effect on measuring sGAG content at 1 uM by Alcian blue staining-based assay | Mus musculus | 2 | ALA4368938 | cell-based format | Scientific Literature | |
12. | ALA4370862 | B | Inhibition of aggrecanase in mouse Primary chondrocytes derived after 0 passages assessed as effect on measuring sGAG content at 1 uM by Alcian blue staining-based assay | Mus musculus | 2 | ALA4368938 | cell-based format | Scientific Literature | |
13. | ALA4370863 | B | Inhibition of MMP2 in mouse Primary chondrocytes derived after 2 passages at 1 uM after 24 hrs by Coomassie blue staining-based zymography assay | Mus musculus | 3 | ALA4368938 | cell-based format | Scientific Literature | |
14. | ALA4370864 | B | Inhibition of MMP9 in mouse Primary chondrocytes derived after 2 passages at 1 uM after 24 hrs by Coomassie blue staining-based zymography assay | Mus musculus | 3 | ALA4368938 | cell-based format | Scientific Literature |