# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4423541 | Binding | Inhibition of recombinant human thymidine phosphorylase expressed in Escherichia coli Rosetta (DE3) cells using thymidine as substrate after 1 min by UV/visible spectrophotometry | Homo sapiens | 14 | ALA4422632 | cell-based format | Scientific Literature | |
2. | ALA4423542 | Binding | Non-competitive inhibition of recombinant human thymidine phosphorylase expressed in Escherichia coli Rosetta (DE3) cells assessed as overall inhibition constant for the enzyme-substrate-inhibitor complex using varying thymidine as substrate after 40 mins by Lineweaver-Burk plot analysis | Homo sapiens | 1 | ALA4422632 | cell-based format | Scientific Literature | |
3. | ALA4423543 | Binding | Non-competitive inhibition of recombinant human thymidine phosphorylase expressed in Escherichia coli Rosetta (DE3) cells assessed as overall inhibition constant for the enzyme-substrate-inhibitor complex using varying inorganic phosphate substrate after 40 mins by Lineweaver-Burk plot analysis | Homo sapiens | 1 | ALA4422632 | cell-based format | Scientific Literature | |
4. | ALA4423544 | ADME | Cytotoxicity against human HepG2 cells assessed as cell viability at 25 uM after 72 hrs by MTT assay relative to control | Homo sapiens | 1 | ALA4422632 | cell-based format | Scientific Literature | |
5. | ALA4423545 | ADME | Cytotoxicity against human HepG2 cells assessed as cell viability at 25 uM after 72 hrs by neutral red uptake-based assay relative to control | Homo sapiens | 1 | ALA4422632 | cell-based format | Scientific Literature | |
6. | ALA4423546 | ADME | Cytotoxicity against human HepG2 cells assessed as cell viability at 50 uM after 72 hrs by MTT assay relative to control | Homo sapiens | 1 | ALA4422632 | cell-based format | Scientific Literature | |
7. | ALA4423547 | ADME | Cytotoxicity against human HepG2 cells assessed as cell viability at 100 uM after 72 hrs by MTT assay relative to control | Homo sapiens | 1 | ALA4422632 | cell-based format | Scientific Literature | |
8. | ALA4423548 | ADME | Cytotoxicity against human HepG2 cells assessed as cell viability at 250 uM after 72 hrs by MTT assay relative to control | Homo sapiens | 1 | ALA4422632 | cell-based format | Scientific Literature | |
9. | ALA4423549 | ADME | Cytotoxicity against human HepG2 cells assessed as cell viability at 500 uM after 72 hrs by MTT assay relative to control | Homo sapiens | 1 | ALA4422632 | cell-based format | Scientific Literature | |
10. | ALA4423550 | ADME | Cytotoxicity against human HepG2 cells assessed as cell viability at 1000 uM after 72 hrs by MTT assay relative to control | Homo sapiens | 1 | ALA4422632 | cell-based format | Scientific Literature | |
11. | ALA4423551 | ADME | Cytotoxicity against human HepG2 cells assessed as cell viability at 50 uM after 72 hrs by neutral red uptake-based assay relative to control | Homo sapiens | 1 | ALA4422632 | cell-based format | Scientific Literature | |
12. | ALA4423552 | ADME | Cytotoxicity against human HepG2 cells assessed as cell viability at 100 uM after 72 hrs by neutral red uptake-based assay relative to control | Homo sapiens | 1 | ALA4422632 | cell-based format | Scientific Literature | |
13. | ALA4423553 | ADME | Cytotoxicity against human HepG2 cells assessed as cell viability at 250 uM after 72 hrs by neutral red uptake-based assay relative to control | Homo sapiens | 1 | ALA4422632 | cell-based format | Scientific Literature | |
14. | ALA4423554 | ADME | Cytotoxicity against human HepG2 cells assessed as cell viability at 500 uM after 72 hrs by neutral red uptake-based assay relative to control | Homo sapiens | 1 | ALA4422632 | cell-based format | Scientific Literature | |
15. | ALA4423555 | ADME | Cytotoxicity against human HepG2 cells assessed as cell viability at 1000 uM after 72 hrs by neutral red uptake-based assay relative to control | Homo sapiens | 1 | ALA4422632 | cell-based format | Scientific Literature | |
16. | ALA4423556 | ADME | Cytotoxicity against African green monkey Vero cells assessed as cell viability at 25 uM after 72 hrs by MTT assay relative to control | Chlorocebus sabaeus | 1 | ALA4422632 | cell-based format | Scientific Literature | |
17. | ALA4423557 | ADME | Cytotoxicity against African green monkey Vero cells assessed as cell viability at 50 uM after 72 hrs by MTT assay relative to control | Chlorocebus sabaeus | 1 | ALA4422632 | cell-based format | Scientific Literature | |
18. | ALA4423558 | ADME | Cytotoxicity against African green monkey Vero cells assessed as cell viability at 100 uM after 72 hrs by MTT assay relative to control | Chlorocebus sabaeus | 1 | ALA4422632 | cell-based format | Scientific Literature | |
19. | ALA4423559 | ADME | Cytotoxicity against African green monkey Vero cells assessed as cell viability at 250 uM after 72 hrs by MTT assay relative to control | Chlorocebus sabaeus | 1 | ALA4422632 | cell-based format | Scientific Literature | |
20. | ALA4423560 | ADME | Cytotoxicity against African green monkey Vero cells assessed as cell viability at 500 uM after 72 hrs by MTT assay relative to control | Chlorocebus sabaeus | 1 | ALA4422632 | cell-based format | Scientific Literature |