# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4343814 | A | Cytotoxicity against human HEK293 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 8 | ALA4342434 | cell-based format | Scientific Literature | |
2. | ALA4343815 | A | Cytotoxicity against human PNT1A cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 8 | ALA4342434 | cell-based format | Scientific Literature | |
3. | ALA4343816 | F | Antiproliferative activity against human PC3 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 8 | ALA4342434 | cell-based format | Scientific Literature | |
4. | ALA4343817 | F | Antiproliferative activity against human DU145 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 8 | ALA4342434 | cell-based format | Scientific Literature | |
5. | ALA4343818 | F | Antiproliferative activity against human KK47 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 8 | ALA4342434 | cell-based format | Scientific Literature | |
6. | ALA4343819 | F | Antiproliferative activity against human T24 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 8 | ALA4342434 | cell-based format | Scientific Literature | |
7. | ALA4343820 | F | Antiproliferative activity against human 786-O cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 8 | ALA4342434 | cell-based format | Scientific Literature | |
8. | ALA4343821 | A | Cmax in Sprague-Dawley rat at 32 mg/kg, po measured after 15 mins by HPLC analysis | Rattus norvegicus | 2 | ALA4342434 | organism-based format | Scientific Literature | |
9. | ALA4343822 | A | AUC (0 to 6 hrs) in Sprague-Dawley rat at 32 mg/kg, po measured upto 6 hrs by HPLC analysis | Rattus norvegicus | 2 | ALA4342434 | organism-based format | Scientific Literature | |
10. | ALA4343823 | F | Antiproliferative activity against mouse MB49 cells assessed as reduction in cell viability after 72 hrs by WST-8 assay | Mus musculus | 3 | ALA4342434 | cell-based format | Scientific Literature | |
11. | ALA4343827 | F | Antitumor activity against mouse MB49 cells xenografted in C57BL/6 mouse bladder cancer model assessed as death rate at 50 mg/ml dosed via intravesical instillation through catheter for 2 hrs and measured after 28 days relative to control | Mus musculus | 1 | ALA4342434 | organism-based format | Scientific Literature | |
12. | ALA4343828 | T | Toxicity in C57BL/6 mouse bladder cancer model xenografted with mouse MB49 cells at 50 mg/ml dosed via intravesical instillation through catheter for 2 hrs and measured for 28 days | Mus musculus | 1 | ALA4342434 | organism-based format | Scientific Literature |