| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4367655 | Functional | Antileishmanial activity Leishmania major MHOM/SA/85/JISH118 after 72 hrs by giemsa staining based light microscopic analysis | Leishmania major | 2 | ALA4364300 | organism-based format | Scientific Literature | |
| 2. | ALA4367656 | Functional | Antileishmanial activity Leishmania panamensis MHOM/PA/67/BOYNTON after 72 hrs by giemsa staining based light microscopic analysis | Leishmania panamensis | 2 | ALA4364300 | organism-based format | Scientific Literature | |
| 3. | ALA4367657 | Functional | Antileishmanial activity Leishmania aethiopica MHOM/ET/84/KH after 72 hrs by giemsa staining based light microscopic analysis | Leishmania aethiopica | 2 | ALA4364300 | organism-based format | Scientific Literature | |
| 4. | ALA4367658 | Functional | Antileishmanial activity Leishmania mexicana MNYC/BZ/62/M379 after 72 hrs by giemsa staining based light microscopic analysis | Leishmania mexicana | 2 | ALA4364300 | organism-based format | Scientific Literature | |
| 5. | ALA4367659 | Functional | Antileishmanial activity Leishmania tropica MHOM/IR/2013/HTD4 after 72 hrs by giemsa staining based light microscopic analysis | Leishmania tropica | 2 | ALA4364300 | organism-based format | Scientific Literature | |
| 6. | ALA4367660 | Functional | Antileishmanial activity Leishmania tropica AO21/p after 72 hrs by giemsa staining based light microscopic analysis | Leishmania tropica | 2 | ALA4364300 | organism-based format | Scientific Literature | |
| 7. | ALA4833899 | ADME | Cytotoxicity against mouse primary peritoneal macrophages measured after 3 days by resazurin staining based fluorometric analysis | Mus musculus | 31 | ALA4831547 | cell-based format | Scientific Literature | |
| 8. | ALA4833900 | Functional | Antileishmanial activity against amastigote stage of Leishmania infantum MHOM/MA(BE)/67/ITMAP263 infected in mouse peritoneal macrophage assessed as reduction in parasite burden incubated for 5 days by Giemsa staining based microscopic analysis | Leishmania infantum | 31 | ALA4831547 | organism-based format | Scientific Literature | |
| 9. | ALA4833911 | ADME | Cytotoxicity against human MRC5 cells measured after 3 days by resazurin staining based fluorometric analysis | Homo sapiens | 30 | ALA4831547 | cell-based format | Scientific Literature | |
| 10. | ALA4833912 | Toxicity | Selectivity index, ratio of CC50 for human MRC5 cells to EC50 for Leishmania infantum MHOM/MA(BE)/67/ITMAP263 | 30 | ALA4831547 | assay format | Scientific Literature | ||
| 11. | ALA4833913 | ADME | Metabolic stability in human liver microsomes assessed as intrinsic clearance at 1 uM measured upto 120 mins in presence of NADPH regenerating system by LC-MS/MS analysis | Homo sapiens | 30 | ALA4831547 | microsome format | Scientific Literature | |
| 12. | ALA4833914 | ADME | Metabolic stability in golden hamster liver microsomes assessed as intrinsic clearance at 1 uM measured upto 120 mins in presence of NADPH regenerating system by LC-MS/MS analysis | Mesocricetus auratus | 30 | ALA4831547 | microsome format | Scientific Literature |
The page will load shortly, Thanks for your patience!