| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4367190 | Binding | Antagonist activity at CCR4 in human CCRF-CEM cells assessed as inhibition of CCL22-mediated chemotaxis in presence of 100% human serum pre-incubated for 30 mins followed by CCL22 addition and measured after 60 mins by chemoTX probe based CellTiter-Glo assay | Homo sapiens | 21 | ALA4364292 | cell-based format | Scientific Literature | |
| 2. | ALA4367191 | Functional | Antagonist activity at human CCR4 expressed in rat chem-5 cells assessed as inhibition of CCL22-induced calcium flux measured at 2.5 secs time interval for 45 secs by fluorescence assay | Homo sapiens | 30 | ALA4364292 | cell-based format | Scientific Literature | |
| 3. | ALA4367199 | ADME | Stability in human hepatocytes assessed as compound remaining incubated for 60 mins under shaking condition by LC-MS/MS analysis | Homo sapiens | 8 | ALA4364292 | cell-based format | Scientific Literature | |
| 4. | ALA4367200 | ADME | Stability in rat hepatocytes assessed as compound remaining incubated for 60 mins under shaking condition by LC-MS/MS analysis | Rattus norvegicus | 8 | ALA4364292 | cell-based format | Scientific Literature |
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