# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4334911 | B | Inhibition of human GSK-3alpha S449A mutant (2 to end residues) at 10 uM using phospho GS2 peptide as substrate after 40 mins in presence of [gamma-33ATP] by scintillation counting method relative to control | Homo sapiens | 80 | ALA4334438 | single protein format | Scientific Literature | |
2. | ALA4334912 | B | Inhibition of human GSK-3alpha S449A mutant (2 to end residues) using phospho GS2 peptide as substrate after 40 mins in presence of [gamma-33ATP] by scintillation counting method | Homo sapiens | 54 | ALA4334438 | single protein format | Scientific Literature | |
3. | ALA4334913 | A | Inhibition of human GSK-3beta H350L mutant (2 to end residues) at 10 uM using phospho GS2 peptide as substrate after 40 mins by [gamma-33ATP] radiometric assay relative to control | Homo sapiens | 48 | ALA4334438 | single protein format | Scientific Literature | |
4. | ALA4334914 | A | Inhibition of human GSK-3beta H350L mutant (2 to end residues) at 10 uM using phospho GS2 peptide as substrate after 40 mins by [gamma-33ATP] radiometric assay | Homo sapiens | 48 | ALA4334438 | single protein format | Scientific Literature | |
5. | ALA4334916 | F | Antiproliferative activity against human HL60 cells assessed as reduction in viability after 3 days by SRB assay | Homo sapiens | 2 | ALA4334438 | cell-based format | Scientific Literature | |
6. | ALA4334917 | F | Antiproliferative activity against human NB4 cells assessed as reduction in viability after 3 days by SRB assay | Homo sapiens | 2 | ALA4334438 | cell-based format | Scientific Literature | |
7. | ALA4334920 | F | Inhibition of colony formation in human HL60 cells preincubated for 72 hrs followed by compound washout and measured after 7 to 10 days | Homo sapiens | 2 | ALA4334438 | cell-based format | Scientific Literature | |
8. | ALA4334921 | F | Inhibition of colony formation in human NB4 cells preincubated for 72 hrs followed by compound washout and measured after 7 to 10 days | Homo sapiens | 2 | ALA4334438 | cell-based format | Scientific Literature | |
9. | ALA4334952 | B | Inhibition of human ABL1 (27 to end residues) assessed as residual activity at 1 uM using EAIYAAPFAKKK as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control | Homo sapiens | 2 | ALA4334438 | single protein format | Scientific Literature | |
10. | ALA4334953 | B | Inhibition of human ABL1 H396P mutant (27 to end residues) assessed as residual activity at 1 uM using EAIYAAPFAKKK as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control | Homo sapiens | 2 | ALA4334438 | single protein format | Scientific Literature | |
11. | ALA4334954 | B | Inhibition of human ABL1 M351T mutant (27 to end residues) assessed as residual activity at 1 uM using EAIYAAPFAKKK as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control | Homo sapiens | 2 | ALA4334438 | single protein format | Scientific Literature | |
12. | ALA4334955 | B | Inhibition of human ABL1 Q252H mutant (27 to end residues) assessed as residual activity at 1 uM using EAIYAAPFAKKK as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control | Homo sapiens | 2 | ALA4334438 | single protein format | Scientific Literature | |
13. | ALA4334956 | B | Inhibition of human ABL1 T315I mutant (27 to end residues) assessed as residual activity at 1 uM using EAIYAAPFAKKK as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control | Homo sapiens | 2 | ALA4334438 | single protein format | Scientific Literature | |
14. | ALA4334957 | B | Inhibition of human ABL1 Y253F mutant (27 to end residues) assessed as residual activity at 1 uM using EAIYAAPFAKKK as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control | Homo sapiens | 2 | ALA4334438 | single protein format | Scientific Literature | |
15. | ALA4334958 | B | Inhibition of human ACK1 (1 to 389 residues) assessed as residual activity at 1 uM using EFPIYDFLPAKKK as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control | Homo sapiens | 2 | ALA4334438 | single protein format | Scientific Literature | |
16. | ALA4334959 | B | Inhibition of human ACTR2A (162 to end residues) assessed as residual activity at 1 uM using casein as substrate incubated for 120 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control | Homo sapiens | 2 | ALA4334438 | single protein format | Scientific Literature | |
17. | ALA4334960 | B | Inhibition of human ALK (1058 to end residues) assessed as residual activity at 1 uM using KKKSPGEYVNIEFG as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control | Homo sapiens | 2 | ALA4334438 | single protein format | Scientific Literature | |
18. | ALA4334961 | B | Inhibition of recombinant human ALK1 (142 to end residues) assessed as residual activity at 1 uM using casein as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control | Homo sapiens | 2 | ALA4334438 | single protein format | Scientific Literature | |
19. | ALA4334962 | B | Inhibition of human ALK2 (147 to end residues) assessed as residual activity at 1 uM using casein as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control | Homo sapiens | 2 | ALA4334438 | single protein format | Scientific Literature | |
20. | ALA4334963 | B | Inhibition of human ALK4 (150 to end residues) assessed as residual activity at 1 uM using casein as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control | Homo sapiens | 2 | ALA4334438 | single protein format | Scientific Literature |