# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4372846 | B | Induction of GFP-tagged Fzd1 (unknown origin) internalization expressed in human U2OS cells at 12.5 after 6 hrs by confocal microscopic method relative to control | Homo sapiens | 9 | ALA4371061 | cell-based format | Scientific Literature | |
2. | ALA4372848 | B | Inhibition of Wnt3A-stimulated Wnt/beta-catenin pathway in HEK293 cells transfected with p8xTOPFlash, Renilla luciferase plasmid pRL-TK and pLKO.1 at 10 uM after 8 hrs by Dual topflash luciferase reporter gene assay relative to control | Homo sapiens | 2 | ALA4371061 | cell-based format | Scientific Literature | |
3. | ALA4372849 | B | Inhibition of Wnt3A-stimulated Wnt/beta-catenin pathway in HEK293 cells transfected with p8xTOPFlash, Renilla luciferase plasmid pRL-TK and pLKO.1 at 5 uM after 8 hrs by Dual topflash luciferase reporter gene assay relative to control | Homo sapiens | 2 | ALA4371061 | cell-based format | Scientific Literature | |
4. | ALA4404535 | F | Antiviral activity against Human adenovirus 5 infected in 293beta5 cells assessed as inhibition of plaque formation at 10 uM incubated for 7 days by GFP reporter gene assay relative to control | Human adenovirus 5 | 55 | ALA4402567 | organism-based format | Scientific Literature | |
5. | ALA4404536 | F | Antiviral activity against Human adenovirus 5 infected in 293beta5 cells assessed as inhibition of plaque formation incubated for 7 days by GFP reporter gene assay | Human adenovirus 5 | 55 | ALA4402567 | organism-based format | Scientific Literature | |
6. | ALA4404537 | A | Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by alamar blue assay | Homo sapiens | 55 | ALA4402567 | cell-based format | Scientific Literature | |
7. | ALA4404538 | T | Selectivity index, ratio of CC50 for cytotoxicity against human A549 cells to IC50 for antiviral activity against Human adenovirus 5 infected in 293beta5 cells assessed as inhibition of plaque formation after 7 days | 55 | ALA4402567 | cell-based format | Scientific Literature |