# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4417321 | B | Modulation activity at CD36 in mouse RAW264.7 cells assessed as inhibition of TLR-2 agonist R-FSL-1-induced NO overproduction relative to control | Mus musculus | 8 | cell-based format | Scientific Literature | ||
2. | ALA4417322 | B | Displacement of photoactivated [125I]-Tyr-Bpa-Ala-hexarelin from CD36 in rat heart purified membranes relative to control | Rattus norvegicus | 8 | cell membrane format | Scientific Literature | ||
3. | ALA4417323 | B | Modulation activity at CD36 in mouse J774 cells assessed as promotion of cholesterol efflux at 100 nM pre-incubated for 17 hrs before apolipoprotein A-I addition for 4 hrs by fluorescent-labeled cholesterol kit based assay relative to control | Mus musculus | 7 | cell-based format | Scientific Literature | ||
4. | ALA4418203 | F | Inhibition of R-FSL-1-induced nitric oxide production in mouse RAW264.7 cells at 10 uM pre-incubated for 1 hr before R-FSL-1 stimulation by fluorescence based assay relative to control | Mus musculus | 12 | cell-based format | Patent Bioactivity Data | ||
5. | ALA4418204 | B | Displacement of [125]-Tyr-Bpa-Ala-Hexarelin from CD36 in Sprague-Dawley rat heart membranes incubated for 60 mins | Rattus norvegicus | 23 | cell membrane format | Patent Bioactivity Data | ||
6. | ALA4418205 | F | Inhibition of R-FSL-1-induced TNFalpha production in mouse RAW264.7 cells at 10 uM pre-incubated for 30 mins before R-FSL-1 stimulation for 4 hrs by ELISA | Mus musculus | 8 | cell-based format | Patent Bioactivity Data | ||
7. | ALA4418206 | F | Inhibition of R-FSL-1-induced CCL2 production in mouse RAW264.7 cells at 10 uM pre-incubated for 30 mins before R-FSL-1 stimulation for 4 hrs by ELISA | Mus musculus | 8 | cell-based format | Patent Bioactivity Data | ||
8. | ALA4418207 | F | Anti-atherosclerotic activity in atherogenic diet fed apoE-/- mouse assessed as reduction in aortic lesions at 300 nmol/kg, sc dosed daily for 8 weeks from from 12 weeks of age relative to control | Mus musculus | 6 | organism-based format | Patent Bioactivity Data | ||
9. | ALA5034722 | B | Modulation of CD36 receptor in mouse RAW 264.7 cells assessed as inhibition of R-FSL-1-induced NO production pretreated for 30 mins followed by R-FSL-1 stimulation measured after 1140 min by fluorescence plate reader assay | Mus musculus | 15 | cell-based format | Scientific Literature | ||
10. | ALA5034723 | B | Modulation of CD36 receptor in mouse RAW 264.7 cells assessed as inhibition of R-FSL-1-induced NO production at competitive receptor binding assay IC50 concentration pretreated for 30 mins followed by R-FSL-1 stimulation measured after 19 hrs by fluorescence plate reader assay relative to R-FSL-1 | Mus musculus | 14 | cell-based format | Scientific Literature | ||
11. | ALA5034724 | B | Modulation of CD36 receptor in mouse RAW 264.7 cells assessed as inhibition of R-FSL-1-induced TNFalpha production pretreated for 30 mins followed by R-FSL-1 stimulation measured after 4 hrs by ELISA | Mus musculus | 15 | cell-based format | Scientific Literature | ||
12. | ALA5034725 | B | Modulation of CD36 receptor in mouse RAW 264.7 cells assessed as inhibition of R-FSL-1-induced TNFalpha production at competitive receptor binding assay IC50 concentration pretreated for 30 mins followed by R-FSL-1 stimulation measured after 19 hrs by ELISA relative to R-FSL-1 | Mus musculus | 14 | cell-based format | Scientific Literature | ||
13. | ALA5034726 | B | Modulation of CD36 receptor in mouse RAW 264.7 cells assessed as inhibition of R-FSL-1-induced CCL-2 production pretreated for 30 mins followed by R-FSL-1 stimulation measured after 4 hrs by ELISA | Mus musculus | 15 | cell-based format | Scientific Literature | ||
14. | ALA5034727 | B | Modulation of CD36 receptor in mouse RAW 264.7 cells assessed as inhibition of R-FSL-1-induced CCl-2 production at competitive receptor binding assay IC50 concentration pretreated for 30 mins followed by R-FSL-1 stimulation measured after 19 hrs by ELISA relative to R-FSL-1 | Mus musculus | 14 | cell-based format | Scientific Literature | ||
15. | ALA5034728 | B | Modulation of CD36 receptor in mouse BMA3.1A7 cells assessed as inhibition of R-FSL-1-induced IL-1beta production pretreated for 30 mins followed by R-FSL-1 stimulation measured after 4 hrs by ELISA | Mus musculus | 15 | cell-based format | Scientific Literature | ||
16. | ALA5034729 | B | Modulation of CD36 receptor in mouse BMA3.1A7 cells assessed as inhibition of R-FSL-1-induced IL-1beta production at competitive receptor binding assay IC50 concentration pretreated for 30 mins followed by R-FSL-1 stimulation measured after 4 hrs by ELISA relative to R-FSL-1 | Mus musculus | 14 | cell-based format | Scientific Literature | ||
17. | ALA5034730 | B | Displacement of [125I]-Tyr-Bpa-Ala-hexarelin from rat CD36 receptor in heart tissue membrane incubated for 60 mins by competitive receptor binding assay | Rattus norvegicus | 14 | cell membrane format | Scientific Literature |