# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4374304 | Binding | Protac activity at CRBN/ IKZF1 in human MM1S cells assessed as IKZF1 degradation by measuring IKZF1/tubulin ratio at 0.1 uM after 16 hrs by Western blot analysis relative to tubulin | Homo sapiens | 7 | ALA4373656 | cell-based format | Scientific Literature | |
2. | ALA5105246 | Physicochemical | Thermodynamic solubility of the compound in phosphate buffer at pH 7 incubated for 1 hr by shake flask based HPLC-UV analysis | 28 | ALA5104112 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA5224294 | Binding | Induction of CRBN degradation in human MM1.S cells assessed as maximum degradation at 100 nM incubated for 24 hrs relative to control | Homo sapiens | 1 | ALA5223100 | cell-based format | Scientific Literature |