# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4431470 | B | Inhibition of recombinant human C-terminal nano luciferase-tagged SLC40A1 expressed in human T-REx-293 cells assessed as decrease in 55Fe-apotransferrin export at 10 uM preincubated for 24 hrs followed by export buffer and compound addition measured after 5 mins by scintillation counting method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
2. | ALA4431471 | B | Inhibition of recombinant human SLC40A1 expressed in human T-REx-293 cells assessed as reduction in ferroportin internalization incubated for 20 hrs by luciferase reporter gene assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
3. | ALA4431472 | B | Inhibition of recombinant human SLC40A1 expressed in human T-REx-293 cells exposed to 4 hrs of doxycycline induction assessed as reduction in ferroportin internalization incubated for 20 hrs by luciferase reporter gene assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA4431473 | B | Inhibition of recombinant human SLC40A1 expressed in human T-REx-293 cells exposed to >4 hrs of doxycycline induction assessed as reduction in ferroportin internalization incubated for 20 hrs by luciferase reporter gene assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature |