# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4416606 | F | Inhibition of LPS-induced serum IL-1beta production in C57BL/6 mouse at 10 mg/kg, ip pretreated before LPS challenge and measured after 2.5 hrs post LPS challenge by ELISA | Mus musculus | 3 | organism-based format | Scientific Literature | ||
2. | ALA4416607 | F | Inhibition of LPS-induced serum TNFalpha production in C57BL/6 mouse at 10 mg/kg, ip pretreated before LPS challenge and measured after 2.5 hrs post LPS challenge by ELISA | Mus musculus | 2 | organism-based format | Scientific Literature | ||
3. | ALA4416608 | B | Inhibition of NLRP3 in mouse J774A.1 cells assessed as inhibition of LPS and ATP-induced IL-1beta production pre-stimulated with LPS for 4.5 hrs before compound addition with ATP for 30 mins by ELISA | Mus musculus | 27 | cell-based format | Scientific Literature | ||
4. | ALA4416609 | B | Inhibition of NLRP3 in mouse peritoneal macrophages assessed as inhibition of LPS and ATP-induced IL-1beta production pre-stimulated with LPS for 4.5 hrs before compound addition with ATP for 30 mins by ELISA | Mus musculus | 3 | single protein format | Scientific Literature | ||
5. | ALA4416610 | B | Inhibition of NLRC4 in mouse J774A.1 cells assessed as inhibition of LPS and poly(dA:dT)-induced IL-1beta production incubated with LPS for 1 hr followed by poly(dA:dT) addition and further incubated for 8 hrs ELISA | Mus musculus | 2 | cell-based format | Scientific Literature | ||
6. | ALA4416612 | B | Inhibition of AIM2 in mouse J774A.1 cells assessed as inhibition of LPS and flagellin-induced IL-1beta production incubated with LPS for 1 hr followed by flagellin addition and further incubated for 6 hrs ELISA | Mus musculus | 2 | cell-based format | Scientific Literature |