| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4405126 | F | Antiproliferative activity against human Hs578T cells assessed as cell growth inhibition measured after 48 hrs by SRB assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 2. | ALA4405132 | B | Inhibition of recombinant human N-terminal GST-tagged HDAC6 (1 to 1125 residues) expressed in baculovirus infected insect cells using fluorogenic peptide p53 residues 379-382 (RHKK(Ac)AMC) as substrate measured after 1 to 2 hrs by fluorescence assay | Homo sapiens | 38 | cell-based format | Scientific Literature | ||
| 3. | ALA4405138 | B | Inhibition of human PI3Kalpha assessed as reduction in PIP3 product complex formation by measuring displacement of biotin-labelled PIP3 from complex using PIP2 as substrate measured after 30 mins in presence of ATP by HTRF assay | Homo sapiens | 23 | single protein format | Scientific Literature | ||
| 4. | ALA4405140 | B | Inhibition of human PI3Kgamma assessed as reduction in PIP3 product complex formation by measuring displacement of biotin-labelled PIP3 from complex using PIP2 as substrate measured after 30 mins in presence of ATP by HTRF assay | Homo sapiens | 26 | single protein format | Scientific Literature | ||
| 5. | ALA4405141 | B | Inhibition of human PI3Kdelta assessed as reduction in PIP3 product complex formation by measuring displacement of biotin-labelled PIP3 from complex using PIP2 as substrate measured after 30 mins in presence of ATP by HTRF assay | Homo sapiens | 34 | single protein format | Scientific Literature | ||
| 6. | ALA4405152 | B | Selectivity index, ratio of IC50 for inhibition of full length recombinant human C-terminal FLAG/His-tagged HDAC1 (1 to 482 residues) expressed in baculovirus infected Sf21 insect cells using fluorogenic peptide p53 residues 379-382 (RHKK(Ac)AMC) as substrate measured after 1 to 2 hrs by fluorescence assay to IC50 for inhibition of recombinant human N-terminal GST-tagged HDAC6 (1 to 1125 residues) expressed in baculovirus infected insect cells using fluorogenic peptide p53 residues 379-382 (RHKK(Ac)AMC) as substrate measured after 1 to 2 hrs by fluorescence assay | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
| 7. | ALA4405153 | A | Permeability of compound in DMSO aqueous buffer at pH 7.4 after 30 mins by PAMPA | 19 | assay format | Scientific Literature | |||
| 8. | ALA4405154 | F | Antiproliferative activity against human CCRF-CEM cells assessed as cell growth inhibition measured after 48 hrs by SRB assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 9. | ALA4405155 | F | Antiproliferative activity against human SR cells assessed as cell growth inhibition measured after 48 hrs by SRB assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 10. | ALA4405156 | F | Antiproliferative activity against human HOP62 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 11. | ALA4405157 | F | Antiproliferative activity against human HOP92 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 12. | ALA4405158 | F | Antiproliferative activity against human HCC2998 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 13. | ALA4405159 | F | Antiproliferative activity against human KM12 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 14. | ALA4405160 | F | Antiproliferative activity against human SNB75 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 15. | ALA4405161 | F | Antiproliferative activity against human U251 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 16. | ALA4405162 | F | Antiproliferative activity against human LOXIMVI cells assessed as cell growth inhibition measured after 48 hrs by SRB assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 17. | ALA4405163 | F | Antiproliferative activity against human M14 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 18. | ALA4405164 | F | Antiproliferative activity against human IGROV1 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 19. | ALA4405165 | F | Antiproliferative activity against human OVCAR3 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 20. | ALA4405166 | F | Antiproliferative activity against human A498 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay | Homo sapiens | 7 | cell-based format | Scientific Literature |
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