# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4426104 | B | Displacement of [Lys2(sCy5),Arg4]-BVD-15 from C-terminal GFP-tagged neuropeptide Y4R (unknown origin) expressed in human 293TR cells measured after 30 mins by fluorescence analysis | Homo sapiens | 12 | ALA4425111 | cell-based format | Scientific Literature | |
2. | ALA4426105 | B | Agonist activity at GFP-tagged neuropeptide Y4R (unknown origin) expressed in HEK293T cells assessed as beta-arrestin2 recruitment measured after 60 mins by H33342 staining-based imaging method relative to PP | Homo sapiens | 9 | ALA4425111 | cell-based format | Scientific Literature | |
3. | ALA4426106 | B | Agonist activity at GFP-tagged neuropeptide Y1R (unknown origin) expressed in HEK293T cells assessed as beta-arrestin2 recruitment measured after 60 mins by H33342 staining-based imaging method | Homo sapiens | 3 | ALA4425111 | cell-based format | Scientific Literature | |
4. | ALA4426108 | B | Agonist activity at GFP-tagged neuropeptide Y4R (unknown origin) expressed in HEK293T cells assessed as beta-arrestin2 recruitment measured after 60 mins by H33342 staining-based imaging method | Homo sapiens | 12 | ALA4425111 | cell-based format | Scientific Literature | |
5. | ALA4426111 | B | Selectivity ratio of IC50 for GFP-tagged neuropeptide Y1R (unknown origin) expressed in HEK293T cells to IC50 for C-terminal GFP-tagged neuropeptide Y4R (unknown origin) expressed in human 293TR cells | Homo sapiens | 3 | ALA4425111 | cell-based format | Scientific Literature | |
6. | ALA4478045 | F | Agonist activity at human NPY Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ assessed as induction of calcium mobilization by aequorin luminescence assay | Homo sapiens | 13 | ALA4477203 | cell-based format | Scientific Literature | |
7. | ALA4478046 | F | Intrinsic activity at human NPY Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ assessed as induction of calcium mobilization by aequorin luminescence assay relative to pancreatic polypeptide | Homo sapiens | 10 | ALA4477203 | cell-based format | Scientific Literature | |
8. | ALA4478047 | F | Agonist activity at human NPY Y4 receptor expressed in HEK293 cells co-expressing CRE-Luc gene assessed as inhibition of forskolin stimulated luciferase activity after 4.5 hrs by luminescence assay | Homo sapiens | 13 | ALA4477203 | cell-based format | Scientific Literature | |
9. | ALA4478048 | F | Intrinsic activity at human NPY Y4 receptor expressed in HEK293 cells co-expressing CRE-Luc gene assessed as inhibition of forskolin stimulated luciferase activity after 4.5 hrs by luminescence assay relative to pancreatic polypeptide | Homo sapiens | 10 | ALA4477203 | cell-based format | Scientific Literature | |
10. | ALA4478049 | B | Displacement of [3H]UR-MK136 from human NPY Y1 receptor expressed in human MCF7 cells by liquid scintillation counting | Homo sapiens | 11 | ALA4477203 | cell-based format | Scientific Literature | |
11. | ALA4478050 | B | Displacement of [3H]propionyl-pNPY from human NPY Y2 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ after 90 mins by liquid scintillation counting | Homo sapiens | 11 | ALA4477203 | cell-based format | Scientific Literature | |
12. | ALA4478051 | B | Displacement of [3H](2R,7R)-10 from human NPY Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ after 90 mins in presence of sodium-free HEPES buffer by liquid scintillation counting | Homo sapiens | 15 | ALA4477203 | cell-based format | Scientific Literature | |
13. | ALA4478052 | B | Displacement of [3H](2R,7R)-10 from human NPY Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ after 90 mins in presence of L-15 medium by liquid scintillation counting | Homo sapiens | 4 | ALA4477203 | cell-based format | Scientific Literature | |
14. | ALA4478053 | F | Antagonist activity at human NPY Y1 receptor expressed in human HEL cells assessed as inhibition of the pNPY-stimulated intracellular [Ca2+] mobilization by Fura-2 based luminescence spectrometry | Homo sapiens | 2 | ALA4477203 | cell-based format | Scientific Literature | |
15. | ALA4478054 | B | Displacement of [3H]18 from human NPY Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ after 90 mins by liquid scintillation counting | Homo sapiens | 6 | ALA4477203 | cell-based format | Scientific Literature | |
16. | ALA4478055 | B | Displacement of [3H]propionyl-pNPY from human NPY Y5 receptor expressed in human HEC1b cells after 120 mins by liquid scintillation counting | Homo sapiens | 11 | ALA4477203 | cell-based format | Scientific Literature |