| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4331180 | F | Quenching activity of compound in pH 7.4 PBS assessed as 4-HNE consumption at 2 mmol/L after 1 hr by HPLC analysis | 6 | assay format | Scientific Literature | |||
| 2. | ALA4331181 | F | Quenching activity of compound in pH 7.4 PBS assessed as 4-HNE consumption at 2 mmol/L after 30 mins by HPLC analysis relative to control | 3 | assay format | Scientific Literature | |||
| 3. | ALA4331182 | A | Cytotoxicity against rat PC12 cells at 1 to 50 mM after 30 mins by MTT assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4331183 | F | Neuroprotective activity against 4-HNE-induced toxicity in rat PC12 cells preincubated for 30 mins followed by compound wash and 4-HNE addition measured after 24 hrs by MTT assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4331184 | F | Neuroprotective activity against 4-HNE-induced toxicity in rat PC12 cells at 30 mM preincubated for 30 mins followed by compound wash and 4-HNE addition measured after 24 hrs by MTT assay relative to control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4331186 | F | Neuroprotective activity against BCCO-induced transient cerebral ischemia in mongolian gerbil hippocampal CA1 region assessed as increase in viable neurons at 20 mg/kg, ip administered 20 mins prior to BCCO treatment and measured after 7 days by hematoxylin and eosin staining-based light microscopic analysis relative to control | Meriones unguiculatus | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA4331187 | F | Neuroprotective activity against BCCO-induced transient cerebral ischemia in mongolian gerbil hippocampal CA1 region assessed as increase in viable neurons at 100 mg/kg, ip administered immediately after BCCO treatment and measured after 7 days by hematoxylin and eosin staining-based light microscopic analysis relative to control | Meriones unguiculatus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA4331188 | F | Neuroprotective activity against BCCO-induced transient cerebral ischemia in mongolian gerbil hippocampal CA1 region assessed as increase in Hsp70 activity at 20 mg/kg, ip administered 20 mins prior to BCCO treatment measured after 24 hrs by immunostaining analysis | Meriones unguiculatus | 1 | organism-based format | Scientific Literature |
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