| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4429040 | F | Protection against tunicamycin induced endoplasmic reticulum stress in rat INS-1 cells assessed as increase in cell viability after 3 days by CellTiter-Glo assay relative to control | Rattus norvegicus | 33 | cell-based format | Scientific Literature | ||
| 2. | ALA4429041 | F | Protection against tunicamycin induced endoplasmic reticulum stress in rat INS-1 cells assessed as increase in cell viability after 3 days by CellTiter-Glo assay | Rattus norvegicus | 33 | cell-based format | Scientific Literature | ||
| 3. | ALA4429042 | F | Protection against tunicamycin induced endoplasmic reticulum stress in rat INS-1 cells assessed as increase in cell viability at 5 uM after 72 hrs by CellTiter-Glo assay | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA4429044 | F | Protection against tunicamycin induced endoplasmic reticulum stress in rat INS-1 cells assessed as increase in cell viability at 2.5 to 20 uM after 72 hrs by MTT assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4429045 | F | Protection against tunicamycin induced endoplasmic reticulum stress in mouse BetaTC6 cells assessed as increase in cell viability after 72 hrs by CellTiter-Glo assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4429046 | F | Protection against tunicamycin induced endoplasmic reticulum stress in mouse BetaTC6 cells assessed as increase in cell viability after 72 hrs by MTT assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4429047 | F | Protection against BFA induced endoplasmic reticulum stress in rat INS-1 cells assessed as increase in cell viability at 20 uM after 72 hrs by CellTiter-Glo assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4429048 | F | Reversal of tunicamycin induced caspase-3 cleavage in rat INS-1 cells at 20 uM after 2 to 24 hrs by Western blot analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4429049 | F | Reversal of tunicamycin induced PARP cleavage in rat INS-1 cells at 20 uM after 2 to 24 hrs by Western blot analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4429050 | F | Protection against tunicamycin induced endoplasmic reticulum stress in rat INS-1 cells assessed as increase in cell viability at 20 uM after 24 hrs by live-cell phase-contrast image analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4429051 | F | Reversal of tunicamycin-induced suppression of INS1 mRNA levels in rat INS-1 cells at 20 uM after 24 hrs by qRT-PCR method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4429052 | F | Reversal of tunicamycin suppressed INS2 mRNA levels in rat INS-1 cells at 20 uM after 24 hrs by qRT-PCR method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4429053 | F | Reversal of tunicamycin-induced suppression of PDX1 mRNA levels in rat INS-1 cells at 20 uM after 24 hrs by qRT-PCR method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4429054 | F | Reversal of tunicamycin-induced suppression of MafA mRNA levels in rat INS-1 cells at 20 uM after 24 hrs by qRT-PCR method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4429055 | F | Suppression of tunicamycin impaired glucose-stimulated insulin secretion in rat INS-1 cells at 10 to 20 uM preincubated for 24 hrs followed by 25 mM glucose addition for 1 hr by ELISA | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4429056 | B | Inhibition of IRE1alpha in rat INS-1 cells assessed as suppression of tunicamycin induced spliced XBP1 mRNA levels at 20 uM after 4 to 24 hrs in by qRT-PCR method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4429057 | B | Inhibition of IRE1alpha in rat INS-1 cells assessed as suppression of tunicamycin induced spliced XBP1 mRNA levels in at 20 uM after 4 to 24 hrs by agarose gel electrophoresis based RT-PCR method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4429058 | B | Inhibition of ATF6 in rat INS-1 cells assessed as suppression of tunicamycin induced Bip mRNA levels at 20 uM after 4 to 24 hrs by qRT-PCR method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4429059 | B | Inhibition of ATF6 in rat INS-1 cells assessed as suppression of tunicamycin induced GRP94 mRNA levels at 20 uM after 4 to 24 hrs by qRT-PCR method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4429060 | B | Inhibition of PERK pathway in rat INS-1 cells assessed as reduction in tunicamycin induced ATF4 mRNA levels at 20 uM after 2 to 24 hrs by qRT-PCR method | Rattus norvegicus | 1 | cell-based format | Scientific Literature |
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