# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4405760 | B | Inhibition of recombinant human 6His-tagged ALDH1A1 expressed in Escherichia coli BL21(DE3) using acetaldehyde as substrate preincubated for 5 mins followed by substrate addition by spectrometric assay | Homo sapiens | 5 | ALA4402591 | assay format | Scientific Literature | |
2. | ALA4405761 | B | Inhibition of recombinant human 6His-tagged ALDH1A1 expressed in Escherichia coli BL21(DE3) at 25 uM using acetaldehyde as substrate measured for 30 mins by spectrometric assay relative to control | Homo sapiens | 16 | ALA4402591 | assay format | Scientific Literature | |
3. | ALA4405762 | B | Inhibition of recombinant human 6His-tagged ALDH1A2 expressed in Escherichia coli BL21(DE3) using acetaldehyde as substrate preincubated for 5 mins followed by substrate addition by spectrometric assay | Homo sapiens | 1 | ALA4402591 | assay format | Scientific Literature | |
4. | ALA4405763 | B | Inhibition of recombinant human 6His-tagged ALDH1A2 expressed in Escherichia coli BL21(DE3) at 25 uM using acetaldehyde as substrate measured for 30 mins by spectrometric assay relative to control | Homo sapiens | 16 | ALA4402591 | assay format | Scientific Literature | |
5. | ALA4405764 | B | Inhibition of recombinant human 6His-tagged ALDH1A3 expressed in Escherichia coli BL21(DE3) using acetaldehyde as substrate preincubated for 5 mins followed by substrate addition by spectrometric assay | Homo sapiens | 15 | ALA4402591 | assay format | Scientific Literature | |
6. | ALA4405765 | B | Inhibition of recombinant human 6His-tagged ALDH1A3 expressed in Escherichia coli BL21(DE3) at 25 uM using acetaldehyde as substrate measured for 30 mins by spectrometric assay | Homo sapiens | 16 | ALA4402591 | assay format | Scientific Literature | |
7. | ALA4405766 | B | Competitive inhibition of recombinant human 6His-tagged ALDH1A3 expressed in Escherichia coli BL21(DE3) using varying level of acetaldehyde as substrate preincubated for 5 mins followed by substrate addition by Michaelis-Menten plot analysis | Homo sapiens | 1 | ALA4402591 | assay format | Scientific Literature | |
8. | ALA4405767 | F | Antiproliferative activity against human PN157 cells measured after 72 hrs by alamar blue assay | Homo sapiens | 7 | ALA4402591 | cell-based format | Scientific Literature | |
9. | ALA4405768 | F | Antiproliferative activity against human MES267 cells measured after 72 hrs by alamar blue assay | Homo sapiens | 7 | ALA4402591 | cell-based format | Scientific Literature | |
10. | ALA4405769 | F | Antiproliferative activity against human MES374 cells measured after 72 hrs by alamar blue assay | Homo sapiens | 7 | ALA4402591 | cell-based format | Scientific Literature | |
11. | ALA4606690 | B | Inhibition of human recombinant ALDH1A3 pre-incubated for 5 mins before acetaldehyde addition by continuous spectrometric assay relative to control | Homo sapiens | 7 | ALA4602736 | single protein format | Scientific Literature |