# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4321462 | B | Inhibition of human DGAT1 | Homo sapiens | 6 | single protein format | Scientific Literature | ||
2. | ALA4321463 | B | Inhibition of mouse DGAT1 | Mus musculus | 6 | single protein format | Scientific Literature | ||
3. | ALA4321464 | P | Lipophilicity, log D of the compound by HPLC analysis | 6 | small-molecule physicochemical format | Scientific Literature | |||
4. | ALA4321465 | B | Inhibition of human ACAT1 | Homo sapiens | 6 | single protein format | Scientific Literature | ||
5. | ALA4321466 | B | Selectivity index, ratio of IC50 for human ACAT1 to IC50 for human DGAT1 | Homo sapiens | 6 | assay format | Scientific Literature | ||
6. | ALA4321467 | F | Reduction in lipid excursion in mouse assessed as change in triglyceride level at 3 mg/kg, po measured at 18 hrs post dose by lipid tolerance test | Mus musculus | 4 | organism-based format | Scientific Literature | ||
7. | ALA4321470 | A | Plasma concentration in mouse at 3 mg/kg, po | Mus musculus | 4 | organism-based format | Scientific Literature | ||
8. | ALA4321471 | A | Stability in rat hepatocytes assessed as epimerization incubated for 2 hrs by UPLC/HRMS analysis | Rattus norvegicus | 4 | cell-based format | Scientific Literature | ||
9. | ALA4321472 | A | Stability in mouse hepatocytes assessed as epimerization incubated for 2 hrs by UPLC/HRMS analysis | Mus musculus | 4 | cell-based format | Scientific Literature | ||
10. | ALA4321473 | A | Stability in human hepatocytes assessed as epimerization incubated for 2 hrs by UPLC/HRMS analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
11. | ALA4321474 | A | Drug metabolism in rat hepatocytes assessed as glucuronide formation incubated for 2 hrs by UPLC/HRMS analysis | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
12. | ALA4321475 | A | Drug metabolism in mouse hepatocytes assessed as glucuronide formation incubated for 2 hrs by UPLC/HRMS analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
13. | ALA4321476 | A | Drug metabolism in human hepatocytes assessed as glucuronide formation incubated for 2 hrs by UPLC/HRMS analysis | Homo sapiens | 2 | cell-based format | Scientific Literature |