| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4345633 | B | Inhibition of human proteasome pre-incubated for 30 mins before Suc-LLVY-AMC substrate addition and measured after 120 mins by fluorescence based assay | Homo sapiens | 8 | ALA4342504 | subcellular format | Scientific Literature | |
| 2. | ALA4345634 | B | Inhibition of HDAC1/2 in human HeLa cell nuclear extracts pre-incubated for 5 mins before fluorogenic substrate Boc-Lys (acetyl)-AMC or Boc-Lys (triflouroacetyl)-AMC addition and measured after 30 mins by fluorescence based assay | Homo sapiens | 16 | ALA4342504 | cell-based format | Scientific Literature | |
| 3. | ALA4345635 | B | Inhibition of HDAC1 (unknown origin) pre-incubated for 5 mins before fluorogenic substrate Boc-Lys (acetyl)-AMC or Boc-Lys (triflouroacetyl)-AMC addition and measured after 30 mins by fluorescence based assay | Homo sapiens | 3 | ALA4342504 | single protein format | Scientific Literature | |
| 4. | ALA4345636 | B | Inhibition of HDAC2 (unknown origin) pre-incubated for 5 mins before fluorogenic substrate Boc-Lys (acetyl)-AMC or Boc-Lys (triflouroacetyl)-AMC addition and measured after 30 mins by fluorescence based assay | Homo sapiens | 3 | ALA4342504 | single protein format | Scientific Literature | |
| 5. | ALA4345637 | B | Inhibition of HDAC3 (unknown origin) pre-incubated for 5 mins before fluorogenic substrate Boc-Lys (acetyl)-AMC or Boc-Lys (triflouroacetyl)-AMC addition and measured after 30 mins by fluorescence based assay | Homo sapiens | 3 | ALA4342504 | single protein format | Scientific Literature | |
| 6. | ALA4345638 | B | Inhibition of HDAC4 (unknown origin) pre-incubated for 5 mins before fluorogenic substrate Boc-Lys (acetyl)-AMC or Boc-Lys (triflouroacetyl)-AMC addition and measured after 30 mins by fluorescence based assay | Homo sapiens | 3 | ALA4342504 | single protein format | Scientific Literature | |
| 7. | ALA4345639 | B | Inhibition of HDAC6 (unknown origin) pre-incubated for 5 mins before fluorogenic substrate Boc-Lys (acetyl)-AMC or Boc-Lys (triflouroacetyl)-AMC addition and measured after 30 mins by fluorescence based assay | Homo sapiens | 3 | ALA4342504 | single protein format | Scientific Literature | |
| 8. | ALA4345640 | B | Inhibition of HDAC8 (unknown origin) pre-incubated for 5 mins before fluorogenic substrate Boc-Lys (acetyl)-AMC or Boc-Lys (triflouroacetyl)-AMC addition and measured after 30 mins by fluorescence based assay | Homo sapiens | 3 | ALA4342504 | single protein format | Scientific Literature | |
| 9. | ALA4345646 | B | Inhibition of class 1 HDAC n human HeLa cell nuclear extracts pre-incubated for 5 mins before fluorogenic substrate Boc-Lys (acetyl)-AMC addition and measured after 30 mins by fluorescence based assay | Homo sapiens | 3 | ALA4342504 | cell-based format | Scientific Literature | |
| 10. | ALA4345647 | B | Inhibition of class 2 HDAC n human HeLa cell nuclear extracts pre-incubated for 5 mins before fluorogenic substrate Boc-Lys (triflouroacetyl)-AMC addition and measured after 30 mins by fluorescence based assay | Homo sapiens | 3 | ALA4342504 | cell-based format | Scientific Literature | |
| 11. | ALA4345648 | F | Antiproliferative activity against human RPMI8226 cells incubated for 48 hrs by MTT assay | Homo sapiens | 4 | ALA4342504 | cell-based format | Scientific Literature | |
| 12. | ALA4345649 | F | Antiproliferative activity against human U266 cells incubated for 48 hrs by MTT assay | Homo sapiens | 4 | ALA4342504 | cell-based format | Scientific Literature | |
| 13. | ALA4345650 | F | Antiproliferative activity against human KM3 cells incubated for 48 hrs by MTT assay | Homo sapiens | 4 | ALA4342504 | cell-based format | Scientific Literature | |
| 14. | ALA4345651 | A | Antiproliferative activity against HUVEC cells incubated for 48 hrs by MTT assay | Homo sapiens | 4 | ALA4342504 | cell-based format | Scientific Literature | |
| 15. | ALA4345652 | A | Antiproliferative activity against human GES-1 cells incubated for 48 hrs by MTT assay | Homo sapiens | 4 | ALA4342504 | cell-based format | Scientific Literature | |
| 16. | ALA4345653 | A | Antiproliferative activity against human HL7702 cells incubated for 48 hrs by MTT assay | Homo sapiens | 4 | ALA4342504 | cell-based format | Scientific Literature | |
| 17. | ALA4345654 | A | Antiproliferative activity against human HET-1A cells incubated for 48 hrs by MTT assay | Homo sapiens | 4 | ALA4342504 | cell-based format | Scientific Literature | |
| 18. | ALA4345655 | F | Induction of apoptosis in human RPMI8226 cells incubated for 24 hrs by Annexin V-FITC/PI staining based flow cytometry | Homo sapiens | 4 | ALA4342504 | cell-based format | Scientific Literature | |
| 19. | ALA4345656 | F | Induction of apoptosis in human RPMI8226 cells assessed as induction of caspase-3/7 activation incubated for 24 hrs by fluorometric assay | Homo sapiens | 4 | ALA4342504 | cell-based format | Scientific Literature | |
| 20. | ALA4345657 | F | Induction of cell cycle arrest in human KM3 cells assessed as reduction in cell cycle progression in S phase at 100 nM incubated for 24 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 4 | ALA4342504 | cell-based format | Scientific Literature |
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