#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4397816	B	Inhibition of RANKL-RANK protein-protein interaction in C57/BL6 mouse bone marrow macrophage assessed as suppression of M-CSF/mRANKL-induced osteoclast differentiation by measuring decrease in multinucleated TRAP+ cells supplemented with fresh medium containing compounds every 2 days for 5 to 6 days by TRAP staining-based microscopic analysis	Mus musculus	5		cell-based format	Scientific Literature
2.	ALA4397817	B	Inhibition of RANKL-RANK protein-protein interaction in C57/BL6 mouse bone marrow macrophage assessed as suppression of M-CSF/mRANKL-induced osteoclastogenesis by measuring reduction in TRAP activity at 5 uM measured after 3 days by colorimetric assay relative to control	Mus musculus	37		protein format	Scientific Literature
3.	ALA4397818	B	Inhibition of RANKL-RANK protein-protein interaction in C57/BL6 mouse bone marrow macrophage assessed as suppression of M-CSF/mRANKL-induced osteoclastogenesis by measuring reduction in cathepsin K mRNA level at 2.5 uM measured after 3 days by Trizol-reagent-based qRT-PCR analysis	Mus musculus	1		protein format	Scientific Literature
4.	ALA4397821	B	Binding affinity to human RANKL by surface plasmon resonance analysis	Homo sapiens	7		single protein format	Scientific Literature
5.	ALA4397823	A	Cytotoxicity against M-CSF-stimulated C57/BL6 mouse bone marrow macrophages assessed as cell viability at 10 uM measured after 2 days by MTT assay (Rvb = 100%)	Mus musculus	4		cell-based format	Scientific Literature
6.	ALA4397824	B	Inhibition of RANKL-RANK protein-protein interaction in C57/BL6 mouse bone marrow macrophage assessed as suppression of M-CSF/mRANKL-induced osteoclast differentiation by measuring decrease in multinucleated TRAP+ cells at 5 uM supplemented with fresh medium containing compounds every 2 days for 5 to 6 days by TRAP staining-based microscopic analysis	Mus musculus	4		cell-based format	Scientific Literature
7.	ALA4397825	B	Inhibition of RANKL-RANK protein-protein interaction in C57/BL6 mouse bone marrow macrophage assessed as suppression of M-CSF/mRANKL-induced osteoclast differentiation by measuring decrease in nuclei size of F-actin ring formation at 5 uM supplemented with fresh medium containing compounds every 2 days for 5 to 6 days by rhodamine phalloidin/DAPI staining-based microscopic analysis	Mus musculus	4		protein format	Scientific Literature
8.	ALA4397826	B	Inhibition of RANKL-RANK protein-protein interaction in C57/BL6 mouse bone marrow macrophage assessed as suppression of M-CSF/mRANKL-induced osteoclast differentiation by measuring decrease in nuclei number of F-actin ring formation at 5 uM supplemented with fresh medium containing compounds every 2 days for 5 to 6 days by rhodamine phalloidin/DAPI staining-based microscopic analysis	Mus musculus	4		protein format	Scientific Literature
9.	ALA4397827	B	Binding affinity to human TNFalpha by surface plasmon resonance analysis	Homo sapiens	1		single protein format	Scientific Literature
10.	ALA4397828	B	Inhibition of RANKL-RANK protein-protein interaction in C57/BL6 mouse bone marrow macrophage assessed as suppression of M-CSF/mRANKL-induced bone resorption at 1 to 5 uM measured after 2 days by toluidine blue staining-based confocal microscopic analysis	Mus musculus	1		protein format	Scientific Literature
11.	ALA4397830	B	Inhibition of RANKL-RANK protein-protein interaction in C57/BL6 mouse bone marrow macrophage assessed as suppression of M-CSF/mRANKL-induced osteoclastogenesis by measuring reduction in TRAP mRNA level at 2.5 uM measured after 3 days by Trizol-reagent-based qRT-PCR analysis	Mus musculus	1		protein format	Scientific Literature
12.	ALA4397831	B	Inhibition of RANKL-RANK protein-protein interaction in C57/BL6 mouse bone marrow macrophage assessed as suppression of M-CSF/mRANKL-induced osteoclastogenesis by measuring reduction in NFATc1 mRNA level at 2.5 uM measured after 3 days by Trizol-reagent-based qRT-PCR analysis	Mus musculus	1		protein format	Scientific Literature
13.	ALA4397832	B	Inhibition of RANKL-RANK protein-protein interaction in C57/BL6 mouse bone marrow macrophage assessed as suppression of M-CSF/mRANKL-induced osteoclastogenesis by measuring reduction in NFATc1 expression measured after 3 days by Western blot analysis	Mus musculus	1		assay format	Scientific Literature
14.	ALA4397833	B	Inhibition of RANKL-RANK protein-protein interaction in C57/BL6 mouse bone marrow macrophage assessed as suppression of M-CSF/mRANKL-induced osteoclastogenesis by measuring reduction in c-fos expression measured after 3 days by Western blot analysis	Mus musculus	1		assay format	Scientific Literature
15.	ALA5126259	F	Anti-osteoporosis activity C57/BL6 mouse bone marrow macrophage cells assessed as inhibition of RANKL-induced osteoclastogenesis at 1 uM measured after 5 to 6 days in presence of M-CSF and RNKL by TRAP staining microscopic analysis	Mus musculus	40		cell-based format	Scientific Literature
16.	ALA5126261	T	Cytotoxicity against C57/BL6 mouse bone marrow macrophage cells assessed as reduction in cell viability at 10 uM incubated for 3 days by CCK8 assay	Mus musculus	43		cell-based format	Scientific Literature
17.	ALA5126275	A	AUC(0 to t) in OVX-induced C57/BL6 mouse model at 3 mg/kg, iv	Mus musculus	2		organism-based format	Scientific Literature
18.	ALA5126276	A	Half life in OVX-induced C57/BL6 mouse model at 3 mg/kg, iv	Mus musculus	2		organism-based format	Scientific Literature
19.	ALA5126277	A	Clearance in OVX-induced C57/BL6 mouse model at 3 mg/kg, iv	Mus musculus	2		organism-based format	Scientific Literature
20.	ALA5126278	A	Oral bioavailability in OVX-induced C57/BL6 mouse model	Mus musculus	2		organism-based format	Scientific Literature