# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4353429 | B | Inhibition of human recombinant GST-tagged EGFR (catalytic domain 695 to end residues) autophosphorylation expressed in baculovirus infected Sf9 cells using poly( Glu,Tyr) 4:1 as substrate at 1 to 10 uM incubated for 60 mins by ELISA | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
2. | ALA4353431 | B | Inhibition of human recombinant GST-tagged HER2 (catalytic domain 676 to end residues) autophosphorylation expressed in baculovirus infected Sf9 cells using poly( Glu, Tyr) 4:1 as substrate at 10 uM incubated for 60 mins by ELISA relative to control | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
3. | ALA4353432 | B | Inhibition of human recombinant GST-tagged HER2 (catalytic domain 676 to end residues) autophosphorylation expressed in baculovirus infected Sf9 cells using poly( Glu, Tyr) 4:1 as substrate at 1 uM incubated for 60 mins by ELISA relative to control | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
4. | ALA4353433 | B | Inhibition of HER2 autophosphorylation in human HCC1954 cells overexpressing HER2 at 0.02 to 2 uM incubated for 1 hr by Western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
5. | ALA4353434 | F | Antiproliferative activity against human A549 cells overexpressing EGFR assessed as reduction in cell viability at 1 to 60 uM incubated for 72 hrs by MTT assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
6. | ALA4353435 | F | Antiproliferative activity against human HCC1954 cells overexpressing HER2 assessed as reduction in cell viability at 1 to 60 uM incubated for 72 hrs by MTT assay | Homo sapiens | 5 | cell-based format | Scientific Literature |