# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4431153 | B | Inhibition of recombinant sPLA2-2A (unknown origin) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate preincubated for 10 mins followed by substrate addition measured after 60 mins by colorimetric method | Homo sapiens | 12 | ALA4428134 | single protein format | Scientific Literature | |
2. | ALA4431154 | B | Inhibition of sPLA2 in human plasma using 1-Hexadecanoyl-2-(1-pyrenedecanoyl)-sn-glycero-3-phosphomethanol as substrate preincubated for 10 mins followed by substrate addition measured after 90 mins by fluorescence assay | Homo sapiens | 11 | ALA4428134 | cell-free format | Scientific Literature | |
3. | ALA4431156 | B | Inhibition of recombinant sPLA2-5 (unknown origin) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate preincubated for 10 mins followed by substrate addition measured after 60 mins by colorimetric method | Homo sapiens | 11 | ALA4428134 | assay format | Scientific Literature | |
4. | ALA4431157 | B | Inhibition of recombinant sPLA2-10 (unknown origin) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate preincubated for 10 mins followed by substrate addition measured after 60 mins by colorimetric method | Homo sapiens | 11 | ALA4428134 | single protein format | Scientific Literature | |
5. | ALA4431160 | P | Solubility of compound in pH 7.4 DMSO/HBSS after 24 hrs by LC-UV/MS analysis | 1 | ALA4428134 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA4431161 | A | Apparent permeability from apical to basolateral side in human Caco2 cells at pH 6.5 | Homo sapiens | 1 | ALA4428134 | cell-based format | Scientific Literature | |
7. | ALA4431162 | A | Intrinsic clearance in human hepatocytes at 1 uM assessed per million cells measured up to 60 mins | Homo sapiens | 6 | ALA4428134 | cell-based format | Scientific Literature | |
8. | ALA4431163 | B | Inhibition of human ERG expressed in CHO cells by patch clamp assay | Homo sapiens | 1 | ALA4428134 | cell-based format | Scientific Literature | |
9. | ALA4431164 | B | Inhibition of human Nav1.5 expressed in CHO cells by patch clamp assay | Homo sapiens | 1 | ALA4428134 | cell-based format | Scientific Literature | |
10. | ALA4431165 | B | Inhibition of human IKs channel expressed in CHO cells by patch clamp assay | Homo sapiens | 1 | ALA4428134 | cell-based format | Scientific Literature | |
11. | ALA4431166 | B | Inhibition of human Kv4.3 expressed in CHO cells by patch clamp assay | Homo sapiens | 1 | ALA4428134 | cell-based format | Scientific Literature | |
12. | ALA4431167 | B | Inhibition of human Cav3.2 expressed in CHO cells by patch clamp assay | Homo sapiens | 1 | ALA4428134 | cell-based format | Scientific Literature | |
13. | ALA4431168 | B | Inhibition of human Cav1.2 expressed in CHO cells by patch clamp assay | Homo sapiens | 1 | ALA4428134 | cell-based format | Scientific Literature | |
14. | ALA4431169 | A | Inhibition of human recombinant CYP1A2 | Homo sapiens | 1 | ALA4428134 | single protein format | Scientific Literature | |
15. | ALA4431170 | A | Inhibition of human recombinant CYP2C8 | Homo sapiens | 1 | ALA4428134 | single protein format | Scientific Literature | |
16. | ALA4431171 | A | Inhibition of human recombinant CYP3A4 | Homo sapiens | 1 | ALA4428134 | single protein format | Scientific Literature | |
17. | ALA4431172 | A | Inhibition of human recombinant CYP2C9 | Homo sapiens | 1 | ALA4428134 | single protein format | Scientific Literature | |
18. | ALA4431173 | A | Inhibition of human recombinant CYP2C19 | Homo sapiens | 1 | ALA4428134 | single protein format | Scientific Literature | |
19. | ALA4431174 | A | Inhibition of human recombinant CYP2D6 | Homo sapiens | 1 | ALA4428134 | single protein format | Scientific Literature | |
20. | ALA4431175 | B | Inhibition of human OATP1B1 expressed in HEK293 cells assessed as reduction in pivastatin uptake | Homo sapiens | 4 | ALA4428134 | cell-based format | Scientific Literature |