# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4323269 | B | Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured every 2.5 mins for 30 mins by Amplex-Red oxidation assay | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
2. | ALA4323270 | B | Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured every 2.5 mins for 30 mins by Amplex-Red oxidation assay | Bos taurus | 32 | tissue-based format | Scientific Literature | ||
3. | ALA4323271 | A | Substrate activity at recombinant human SSAO assessed as compound oxidation by measuring oxidative turnover at 30 uM measured for 40 mins by horseradish peroxidase-coupled amplex red reagent-based fluorometric assay relative to DMSO | Homo sapiens | 22 | single protein format | Scientific Literature | ||
4. | ALA4323272 | A | Substrate activity at AOC4 in dog serum assessed as compound oxidation by measuring oxidative turnover at 30 uM measured for 40 mins by horseradish peroxidase-coupled amplex red reagent-based fluorometric assay relative to DMSO | Canis lupus familiaris | 15 | cell-free format | Scientific Literature | ||
5. | ALA4323274 | B | Selectivity index, ratio of pIC50 for recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells to pIC50 for LOX in bovine aorta | 2 | cell-based format | Scientific Literature | |||
6. | ALA4323275 | B | Displacement of [3H]PK11195 from human recombinant peripheral benzodiazepine receptor at 10 uM incubated for 15 mins by scintillation counting method | Homo sapiens | 1 | assay format | Scientific Literature | ||
7. | ALA4323276 | B | Inhibition of recombinant human LOXL2 assessed as inhibition of collagen cross linking compound replenishment for 5 days and measured on day 7 by UPLC-ESI-MS/MS analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
8. | ALA4323277 | B | Inhibition of LOXL2 in human IMR90 cells using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured every 2.5 mins for 30 mins by Amplex-Red oxidation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA4323278 | B | Inhibition of recombinant mouse C-terminal His-tagged LOLX2 (26-776 residues) expressed in mouse myeloma cells using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured every 2.5 mins for 30 mins by Amplex-Red oxidation assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
10. | ALA4323279 | B | Inhibition of recombinant rat LOLX2 using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured every 2.5 mins for 30 mins by Amplex-Red oxidation assay | Rattus norvegicus | 1 | single protein format | Scientific Literature | ||
11. | ALA4323280 | B | Inhibition of recombinant human MAOA expressed in baculovirus infected in BTI cells using tyramine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured every 2.5 mins for 30 mins by Amplex-Red oxidation assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
12. | ALA4323281 | B | Inhibition of recombinant human MAOB expressed in baculovirus infected in BTI cells using benzylamine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured every 2.5 mins for 30 mins by Amplex-Red oxidation assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
13. | ALA4323282 | B | Inhibition of recombinant human SSAO using benzylamine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured every 2.5 mins for 30 mins by Amplex-Red oxidation assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
14. | ALA4323283 | B | Inhibition of recombinant human DAO using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured every 2.5 mins for 30 mins by Amplex-Red oxidation assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
15. | ALA4323284 | B | Inhibition of LOX in human IMR90 cells using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured every 2.5 mins for 30 mins by Amplex-Red oxidation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
16. | ALA4323285 | B | Inhibition of LOX in mouse lung fibroblast cells using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured every 2.5 mins for 30 mins by Amplex-Red oxidation assay | Mus musculus | 1 | assay format | Scientific Literature | ||
17. | ALA4323286 | B | Inhibition of recombinant human LOXL1 using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured every 2.5 mins for 30 mins by Amplex-Red oxidation assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
18. | ALA4323287 | B | Inhibition of recombinant C-terminal His-tagged human LOXL3 (1 to 753 residues) expressed in CHO cells using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured every 2.5 mins for 30 mins by Amplex-Red oxidation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
19. | ALA4323288 | B | Inhibition of recombinant human LOXL4 using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured every 2.5 mins for 30 mins by Amplex-Red oxidation assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
20. | ALA4323289 | A | Protein binding in rat plasma | Rattus norvegicus | 1 | cell-free format | Scientific Literature |