#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4372253	B	Inhibition of recombinant 6His-Tev-tagged LRRK2 (1326 to 2527) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-RLGRDKYKTLRQIRQGNTKQR-OH as substrate preincubated for 30 mins followed by substrate addition and measured after 2 hrs by TR-FRET assay	Homo sapiens	26	ALA4371037	cell-based format	Scientific Literature
2.	ALA4372254	P	Lipophilicity, log D of the compound at pH 7.4 by chromatographic method		26	ALA4371037	small-molecule physicochemical format	Scientific Literature
3.	ALA4372255	P	Kinetic solubility of the compound		26	ALA4371037	small-molecule physicochemical format	Scientific Literature
4.	ALA4372256	A	Intrinsic clearance in human liver microsomes	Homo sapiens	20	ALA4371037	microsome format	Scientific Literature
5.	ALA4372257	A	Ratio of permeability across apical to basolateral side in MDCK2-MDR1 cells transduced with BacMam2-BCRP in presence of P-gp inhibitor GF120918 to absence of GF120918	Canis lupus familiaris	15	ALA4371037	cell-based format	Scientific Literature
6.	ALA4372258	A	Passive permeability across apical to basolateral side in MDCK2-MDR1 cells transduced with BacMam2-BCRP at 3 uM after 90 mins in presence of P-gp inhibitor GF120918 by Transwell assay	Canis lupus familiaris	15	ALA4371037	cell-based format	Scientific Literature
7.	ALA4372261	B	Inhibition of parkinson's patient-derived LRRK2 G2019S mutant	Homo sapiens	2	ALA4371037	single protein format	Scientific Literature
8.	ALA4372262	B	Inhibition of human lymphoblastoid cell-derived LRRK2	Homo sapiens	2	ALA4371037	single protein format	Scientific Literature
9.	ALA4372263	B	Inhibition of MKK1 (unknown origin) at 1 uM by radioactivity-based assay relative to control	Homo sapiens	1	ALA4371037	single protein format	Scientific Literature
10.	ALA4372265	A	Fraction unbound in rat blood	Rattus norvegicus	2	ALA4371037	tissue-based format	Scientific Literature
11.	ALA4372266	A	Fraction unbound in rat brain	Rattus norvegicus	2	ALA4371037	tissue-based format	Scientific Literature
12.	ALA4372267	A	Binding affinity to human serum albumin assessed as unbound fraction	Homo sapiens	2	ALA4371037	single protein format	Scientific Literature
13.	ALA4372268	A	Inhibition of human CYP3A4 using atorvastatin as substrate	Homo sapiens	2	ALA4371037	single protein format	Scientific Literature
14.	ALA4372269	A	Activation of human PXR	Homo sapiens	2	ALA4371037	single protein format	Scientific Literature
15.	ALA4372270	A	Inhibition of OATP1B1 (unknown origin)	Homo sapiens	2	ALA4371037	single protein format	Scientific Literature
16.	ALA4372271	B	Inhibition of human ERG by IonWork assay	Homo sapiens	2	ALA4371037	single protein format	Scientific Literature
17.	ALA4372272	F	In vivo inhibition of LRRK2 phosphorylation at Ser935 residue in naive rat brain at 5 mg/kg, iv administered as bolus dose followed by 5 ml/kg/hr iv infusion for 4 hrs by Western blot analysis relative to control	Rattus norvegicus	1	ALA4371037	organism-based format	Scientific Literature
18.	ALA4372273	F	In vivo inhibition of LRRK2 phosphorylation at Ser935 residue in naive rat kidney at 5 mg/kg, iv administered as bolus dose followed by 5 ml/kg/hr iv infusion for 4 hrs by Western blot analysis relative to control	Rattus norvegicus	1	ALA4371037	organism-based format	Scientific Literature
19.	ALA4372274	F	In vivo inhibition of LRRK2 phosphorylation at Ser935 residue in naive rat spleen at 5 mg/kg, iv administered as bolus dose followed by 5 ml/kg/hr iv infusion for 4 hrs by Western blot analysis relative to control	Rattus norvegicus	1	ALA4371037	organism-based format	Scientific Literature
20.	ALA4372275	A	Drug level in naive rat blood at 5 mg/kg, iv administered as bolus dose followed by 5 ml/kg/hr iv infusion for 4 hrs	Rattus norvegicus	1	ALA4371037	organism-based format	Scientific Literature