#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4325024	F	Antibacterial activity against Escherichia coli ATCC 25922 assessed as reduction in bacterial growth by broth microdilution method	Escherichia coli	29	ALA4321867	organism-based format	Scientific Literature
2.	ALA4325025	F	Antibacterial activity against quinolone-resistant Klebsiella pneumoniae T6474 expressing broad spectrum beta-lactamase assessed as reduction in bacterial growth by broth microdilution method	Klebsiella pneumoniae	29	ALA4321867	organism-based format	Scientific Literature
3.	ALA4325026	F	Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 assessed as reduction in bacterial growth by broth microdilution method	Pseudomonas aeruginosa	29	ALA4321867	organism-based format	Scientific Literature
4.	ALA4325027	B	Inhibition of recombinant Escherichia coli LpxC (1 to 300 residues) C125S mutant expressed in Escherichia coli BL21 AI assessed as change in melting temperature at 25 uM by Sypro orange dye based differential scanning fluorimetry	Escherichia coli	21	ALA4321867	assay format	Scientific Literature
5.	ALA4325028	B	Inhibition of recombinant Pseudomonas aeruginosa LpxC (1 to 299 residues) C40S mutant expressed in Escherichia coli BL21 AI assessed as change in melting temperature at 25 uM by Sypro orange dye based differential scanning fluorimetry	Pseudomonas aeruginosa	21	ALA4321867	assay format	Scientific Literature
6.	ALA4325029	P	n-Octanol/phopshate buffer partition coefficient, log D of the compound at pH 7.4 by LC/UV analysis		29	ALA4321867	small-molecule physicochemical format	Scientific Literature
7.	ALA4325030	P	Dissociation constant, pKa of compound by UV metric assay		20	ALA4321867	small-molecule physicochemical format	Scientific Literature
8.	ALA4325031	P	Solubility of compound at pH 4 incubated for 24 hrs by LC/UV analysis		29	ALA4321867	small-molecule physicochemical format	Scientific Literature
9.	ALA4325032	P	Solubility of compound at pH 7 incubated for 24 hrs by LC/UV analysis		29	ALA4321867	small-molecule physicochemical format	Scientific Literature
10.	ALA4325033	P	Solubility of compound at pH 9 incubated for 24 hrs by LC/UV analysis		29	ALA4321867	small-molecule physicochemical format	Scientific Literature
11.	ALA4325034	A	Metabolic stability in rat hepatocytes assessed as total intrinsic clearance at 1 uM measured per million cells	Rattus norvegicus	12	ALA4321867	cell-based format	Scientific Literature
12.	ALA4325035	A	Metabolic stability in rat liver microsomes assessed as total intrinsic clearance at 1 uM	Rattus norvegicus	12	ALA4321867	microsome format	Scientific Literature
13.	ALA4325036	F	In vivo antibacterial activity against Escherichia coli ATCC 25922 A-935 infected in NMRI or ICR CD1 mouse neutropenic thigh infection model assessed as change in log10CFU at 150 mg/kg, sc administered 2 hrs post infection and measured per thigh after 24 hrs by serial dilution method	Escherichia coli	9	ALA4321867	organism-based format	Scientific Literature
14.	ALA4325037	A	Protein binding in mouse plasma at 1 uM by rapid equilibrium dialysis method	Mus musculus	9	ALA4321867	cell-free format	Scientific Literature
15.	ALA4325039	A	AUC (0 to 24 hrs) in mouse at 150 mg/kg, sc measured up to 24 hrs by LC-MS/MS analysis	Mus musculus	8	ALA4321867	organism-based format	Scientific Literature
16.	ALA4325041	A	Free AUC (0 to 24 hrs) in mouse at 150 mg/kg, sc measured up to 24 hrs by LC-MS/MS analysis	Mus musculus	8	ALA4321867	organism-based format	Scientific Literature
17.	ALA4325042	A	Metabolic stability in human hepatocytes assessed as total intrinsic clearance at 1 uM measured per million cells	Homo sapiens	7	ALA4321867	cell-based format	Scientific Literature
18.	ALA4325043	A	Metabolic stability in human liver microsomes assessed as total intrinsic clearance at 1 uM	Homo sapiens	7	ALA4321867	microsome format	Scientific Literature
19.	ALA4325044	A	Protein binding in rat plasma at 1 uM by rapid equilibrium dialysis method	Rattus norvegicus	7	ALA4321867	cell-free format	Scientific Literature
20.	ALA4325045	A	Unbound clearance in Wistar rat at 10 mg/kg, iv measured up to 24 hrs by LC/MS/MS analysis	Rattus norvegicus	6	ALA4321867	organism-based format	Scientific Literature