# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4324950 | Binding | Agonist activity at human IR-beta signalling expressed in mouse 3T3 cells assessed as AKT phosphorylation at Ser473 residue after 30 mins by HTRF assay | Homo sapiens | 1 | ALA4321864 | cell-based format | Scientific Literature | |
2. | ALA4324951 | Functional | Hypoglycemic activity in C57BL/6 mouse assessed as reduction in blood glucose level at 0.75 U/kg, sc after 10 to 60 mins by insulin tolerance test | Mus musculus | 1 | ALA4321864 | organism-based format | Scientific Literature | |
3. | ALA4324952 | Physicochemical | Stability of compound in PBS assessed as aggregation at 1 mg/ml incubated for 100 hrs under shaking condition | 1 | ALA4321864 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA4324953 | ADME | Metabolic stability in human serum assessed as parent compound remaining at 1 mg/ml after 24 hrs by RP-HPLC analysis | Homo sapiens | 1 | ALA4321864 | cell-free format | Scientific Literature | |
5. | ALA4324954 | Physicochemical | Thermal stability of compound in PBS at 1 mg/ml at 60 degC after 4 days by HPLC analysis | 1 | ALA4321864 | small-molecule physicochemical format | Scientific Literature |