| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4358319 | F | Antiplasmodial activity against luciferase expressing Plasmodium berghei sporozoites infected in human HuH7 cells assessed as reduction in parasite load at 1 to 10 uM preincubated for 1 hr followed by parasite infection and measured after 46 hrs by bioluminescence assay | Plasmodium berghei | 5 | ALA4354848 | organism-based format | Scientific Literature | |
| 2. | ALA4358320 | F | Antiplasmodial activity against luciferase expressing Plasmodium berghei sporozoites infected in human HuH7 cells assessed as reduction in parasite load preincubated for 1 hr followed by parasite infection and measured after 46 hrs by bioluminescence assay | Plasmodium berghei | 6 | ALA4354848 | organism-based format | Scientific Literature | |
| 3. | ALA4358321 | A | Cytotoxicity against human HuH7 cells infected with luciferase expressing Plasmodium berghei sporozoites assessed as reduction in cell viability preincubated for 1 hr followed by parasite infection and measured after 48 hrs by alamar blue assay | Homo sapiens | 5 | ALA4354848 | cell-based format | Scientific Literature | |
| 4. | ALA4358322 | F | Potency index, ratio of ivermectin IC50 to test compound IC50 for antiplasmodial activity against luciferase expressing Plasmodium berghei sporozoites infected in human HuH7 cells | Plasmodium berghei | 1 | ALA4354848 | organism-based format | Scientific Literature | |
| 5. | ALA4358323 | F | Antiplasmodial activity against chloroquine-sensitive ring-stage synchronized cultures of Plasmodium falciparum NF54 incubated for 48 hrs by SYBR green I dye based flow cytometry | Plasmodium falciparum | 6 | ALA4354848 | organism-based format | Scientific Literature | |
| 6. | ALA4358324 | F | Potency index, ratio of ivermectin IC50 to test compound IC50 for antiplasmodial activity against chloroquine-sensitive ring-stage synchronized cultures of Plasmodium falciparum NF54 | Plasmodium falciparum | 3 | ALA4354848 | organism-based format | Scientific Literature | |
| 7. | ALA4358325 | F | Insecticidal activity against compound treated Balb/c mouse blood fed Anopheles stephensi assessed as effect on mosquito survival at 1 mg/kg, po administered via gavage 24 hrs prior to blood feed for 20 mins under dark condition and measured daily up to 14 days post blood feed | Anopheles stephensi | 3 | ALA4354848 | organism-based format | Scientific Literature |
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