# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4323097 | Binding | Displacement of trimethylated biotinylated histone H3 peptide from recombinant human His-tagged SPIN1 (26 to 262 residues) expressed in Escherichia coli BL21 (DE3) incubated for 30 mins followed by peptide addition and measured after 1 hr by Alphascreen method | Homo sapiens | 18 | ALA4321817 | assay format | Scientific Literature | |
2. | ALA4323098 | Binding | Inhibition of G9a (unknown origin) by scintillation proximity Assay | Homo sapiens | 12 | ALA4321817 | single protein format | Scientific Literature | |
3. | ALA4323099 | Binding | Inhibition of C-terminal Halotag-histone 3.3 tagged SPIN1 (unknown origin) transfected in human U2OS cells cotransfected with nano-luciferase at 1 uM using NanoBRET Nano-Glo substrate as substrate incubated for 24 hrs by NanoBRET assay | Homo sapiens | 6 | ALA4321817 | cell-based format | Scientific Literature | |
4. | ALA4323100 | ADME | Cytotoxicity against human U2OS cells assessed as reduction in cell viability at >3 uM incubated for 2 days by propidium iodide staining based assay | Homo sapiens | 6 | ALA4321817 | cell-based format | Scientific Literature |