# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4404677 | B | Inhibition of recombinant GSTO1-1 (unknown origin) expressed in Escherichia coli assessed as Kinact using S-(4-nitrophenacyl)glutathione as substrate preincubated for 1 to 6 mins followed by substrate addition by spectrophotmetric analysis | Homo sapiens | 10 | assay format | Scientific Literature | ||
2. | ALA4404678 | B | Inhibition of recombinant GSTO1-1 (unknown origin) expressed in Escherichia coli using S-(4-nitrophenacyl)glutathione as substrate preincubated for 2 mins followed by substrate addition by 4-NPG assay | Homo sapiens | 33 | assay format | Scientific Literature | ||
3. | ALA4404679 | A | Drug level in Swiss mouse plasma at 30 mg/kg, ip after 5 mins by UPLC-MS analysis | Mus musculus | 2 | organism-based format | Scientific Literature | ||
4. | ALA4404680 | B | Inhibition of recombinant GSTO1-1 (unknown origin) expressed in Escherichia coli assessed as inhibitor constant using S-(4-nitrophenacyl)glutathione as substrate preincubated for 1 to 6 mins followed by substrate addition by spectrophotmetric analysis | Homo sapiens | 10 | assay format | Scientific Literature | ||
5. | ALA4404681 | B | Inhibition of recombinant GSTO1-1 (unknown origin) expressed in Escherichia coli assessed as Kinact/Ki ratio using S-(4-nitrophenacyl)glutathione as substrate preincubated for 1 to 6 mins followed by substrate addition by spectrophotmetric analysis | Homo sapiens | 10 | assay format | Scientific Literature | ||
6. | ALA4404682 | B | Inhibition of GSTO1-1 in mouse bone marrow derived macrophage cells assessed as reduction in LPS-induced IL-1beta release by measuring IL1 beta level at 5 uM pretreated with LPS for 3 hrs followed by compound addition and measured after 1 hr by ELISA relative to control | Mus musculus | 11 | assay format | Scientific Literature | ||
7. | ALA4404691 | A | Drug concentration in Swiss mouse plasma at 30 mg/kg, ip measured up to 2 hrs post dose by UPLC-MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature |