| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4411529 | P | Octanol/water phosphate buffer partition coefficient, log D of compound at pH 7.4 by shake-flask method | 19 | small-molecule physicochemical format | Scientific Literature | |||
| 2. | ALA4411534 | A | Passive apparent permeability from apical to basolateral side in RRCK cells | Canis lupus familiaris | 6 | cell-based format | Scientific Literature | ||
| 3. | ALA4411535 | P | Thermodynamic equilibrium solubility of the compound at pH 7.64 phosphate buffer saline by UPLC analysis | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 4. | ALA4411536 | P | Solubility of compound in fasted state simulated intestinal fluid | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 5. | ALA4411537 | P | Solubility of compound in fed state simulated intestinal fluid | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 6. | ALA4411543 | A | Unbound intrinsic clearance in human liver microsomes assessed as per mg protein | Homo sapiens | 1 | microsome format | Scientific Literature | ||
| 7. | ALA4411544 | A | Unbound intrinsic clearance in human hepatocytes assessed as per million cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4411545 | A | Fraction unbound in rat plasma | Rattus norvegicus | 1 | cell-free format | Scientific Literature | ||
| 9. | ALA4411546 | A | Fraction unbound in human plasma | Homo sapiens | 1 | cell-free format | Scientific Literature | ||
| 10. | ALA4411547 | A | Blood to plasma partition coefficient of the compound in human | Homo sapiens | 1 | cell-free format | Scientific Literature | ||
| 11. | ALA4411548 | B | Inhibition of recombinant human VEGFR2 using Ulight-CAGAGAIETDKEYYTVKD as substrate after 60 mins | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA4411549 | B | Inhibition of N-terminal GST tagged human TYK2 (871 to 1187 end residues) catalytic domain expressed in baculovirus expression system at 1 uM in presence of ATP at its Km level relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 13. | ALA4411550 | B | Inhibition of N-terminal GST tagged human JAK1 (850 to 1154 end residues) catalytic domain expressed in baculovirus expression system at 1 uM in presence of ATP at its Km level relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 14. | ALA4411551 | B | Inhibition of N-terminal His tagged human JAK2 (826 to 1132 end residues) catalytic domain expressed in baculovirus expression system at 1 uM in presence of ATP at its Km level relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 15. | ALA4411552 | B | Inhibition of TPX2 activated N-terminal GST tagged full length human AurA (1 to 403 end residues) expressed in baculovirus expression system at 1 uM in presence of ATP at its Km level relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 16. | ALA4411553 | B | Inhibition of N-terminal GST tagged human TNK1 (106 to 390 residues) catalytic domain expressed in baculovirus expression system at 1 uM in presence of ATP at its Km level relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 17. | ALA4411554 | B | Inhibition of N-terminal His tagged human JAK3 (795 to 1124 end residues) catalytic domain expressed in baculovirus expression system at 1 uM in presence of ATP at its Km level relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 18. | ALA4411555 | B | Inhibition of N-terminal GST tagged full length human QIK (1 to 926 end residues) expressed in baculovirus expression system at 1 uM in presence of ATP at its Km level relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 19. | ALA4411556 | B | Inhibition of N-terminal GST tagged human ACK (110 to 476 residues) catalytic domain expressed in baculovirus expression system at 1 uM in presence of ATP at its Km level relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 20. | ALA4411557 | B | Inhibition of N-terminal GST tagged human PDGFRalpha (550 to 1089 end residues) catalytic domain T674I mutant expressed in baculovirus expression system at 1 uM in presence of ATP at its Km level relative to control | Homo sapiens | 1 | assay format | Scientific Literature |
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