#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4362357	A	Cytotoxicity against human SH-SY5Y cells assessed as cell viability at 1 uM measured after 48 hrs by MTT assay relative to control	Homo sapiens	18		cell-based format	Scientific Literature
2.	ALA4362358	A	Cytotoxicity against human SH-SY5Y cells measured after 48 hrs by MTT assay	Homo sapiens	18		cell-based format	Scientific Literature
3.	ALA4362359	B	Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measured for 1 hr by fluorescence assay	Mus musculus	18		assay format	Scientific Literature
4.	ALA4362360	A	Permeability across apical side to basolateral side in human Caco2 cells at 30 uM after 4 hrs by HPLC analysis	Homo sapiens	5		cell-based format	Scientific Literature
5.	ALA4362361	A	Half-life in BALB/c mouse at 10 mg/kg, iv administered as single dose measured after 24 hrs by LC-ESI/MS analysis	Mus musculus	2		organism-based format	Scientific Literature
6.	ALA4362362	A	AUC in BALB/c mouse at 10 mg/kg, iv administered as single dose measured after 24 hrs by LC-ESI/MS analysis	Mus musculus	2		organism-based format	Scientific Literature
7.	ALA4362363	A	Clearance in BALB/c mouse at 10 mg/kg, iv administered as single dose measured after 24 hrs by LC-ESI/MS analysis	Mus musculus	2		organism-based format	Scientific Literature
8.	ALA4362364	A	Volume of distribution in BALB/c mouse at 10 mg/kg, iv administered as single dose measured after 24 hrs by LC-ESI/MS analysis	Mus musculus	2		organism-based format	Scientific Literature
9.	ALA4362365	P	Kinetic aqueous solubility of the compound in 80:20 PBS/acetonitrile solution at 200 to 500 uM by HTS assay		10		small-molecule physicochemical format	Scientific Literature
10.	ALA4362366	P	Thermodynamic solubility of compound in water after 24 hrs by LC-UV based shake flask method		2		small-molecule physicochemical format	Scientific Literature
11.	ALA4362367	A	Metabolic stability in human liver microsomes assessed as parent compound remaining at 50 uM in absence of NADPH for 60 mins by LC-ESI/MS analysis	Homo sapiens	2		microsome format	Scientific Literature
12.	ALA4362368	A	Metabolic stability in Wistar Han rat liver microsomes assessed as parent compound remaining at 50 uM in absence of NADPH for 60 mins by LC-ESI/MS analysis	Rattus norvegicus	2		microsome format	Scientific Literature
13.	ALA4362371	T	Genotoxicity in human primary lymphocytes assessed as induction of DNA damage up to 500 uM by GreenScreen assay	Homo sapiens	1		cell-based format	Scientific Literature
14.	ALA4362373	T	Toxicity in Crl:CD Sprague-Dawley rat retina at 100 mg/kg, ip administered once daily for 5 days by hematoxylin and eosin staining based microscopic analysis	Rattus norvegicus	2		organism-based format	Scientific Literature
15.	ALA4362375	T	Toxicity in Crl:CD Sprague-Dawley rat heart assessed as hypereosinophilia at 100 mg/kg, ip administered once daily for 5 days by hematoxylin and eosin staining based microscopic analysis	Rattus norvegicus	2		organism-based format	Scientific Literature
16.	ALA4362376	T	Toxicity in Crl:CD Sprague-Dawley rat heart assessed as increase in cardiomyocytes cytoplasmic vacuolation at 100 mg/kg, ip administered once daily for 5 days by hematoxylin and eosin staining based microscopic analysis	Rattus norvegicus	2		organism-based format	Scientific Literature
17.	ALA4362377	T	Toxicity in Crl:CD Sprague-Dawley rat heart assessed as interstitial expansion at 100 mg/kg, ip administered once daily for 5 days by hematoxylin and eosin staining based microscopic analysis	Rattus norvegicus	2		organism-based format	Scientific Literature
18.	ALA4362380	F	Antitumor activity against mouse 4T1 cells implanted in BALB/c mouse assessed as reduction in tumour volume at 10 mg/kg, ip bid for 12 days by vernier caliper method	Mus musculus	2		organism-based format	Scientific Literature
19.	ALA4362381	F	Antitumor activity against mouse 4T1 cells implanted in BALB/c mouse assessed as reduction in tumor weight at 10 mg/kg, ip bid for 12 days	Mus musculus	2		organism-based format	Scientific Literature
20.	ALA4362382	F	Antitumor activity against mouse 4T1 cells implanted in Balb/c mouse mouse assessed as inhibition of tumor metastasis at 10 mg/kg, ip bid for 12 days measured post last dose by crystal violet staining based thioguanine clonogenic assay	Mus musculus	2		organism-based format	Scientific Literature