| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4387828 | B | Potency index, ratio of EDTA IC50 to test compound IC50 for Stenotrophomonas maltophilia NDM1 expressed in Escherichia coli BL21 (DE3) expressing measured after 15 minutes at interval of 60s | Stenotrophomonas maltophilia | 1 | ALA4387701 | assay format | Scientific Literature | |
| 2. | ALA4387829 | B | Inhibition of NDM1 in Escherichia coli isolate 8 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC after 24 hrs by broth microdilution assay (Rvb = 320 ug/ml) | Escherichia coli | 3 | ALA4387701 | assay format | Scientific Literature | |
| 3. | ALA4387830 | B | Inhibition of NDM1 in Citrobacter freundii clinical isolate 7 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC after 24 hrs by broth microdilution assay (Rvb = 80 ug/ml) | Citrobacter freundii | 3 | ALA4387701 | assay format | Scientific Literature | |
| 4. | ALA4387831 | B | Inhibition of NDM1 in Enterobacter cloacae isolate 6 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC after 24 hrs by broth microdilution assay (Rvb = 320 ug/ml) | Enterobacter cloacae | 3 | ALA4387701 | assay format | Scientific Literature | |
| 5. | ALA4387832 | B | Inhibition of NDM1 in Enterobacter cloacae isolate 5 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC after 24 hrs by broth microdilution assay (Rvb = 640 ug/ml) | Enterobacter cloacae | 3 | ALA4387701 | assay format | Scientific Literature | |
| 6. | ALA4387833 | B | Inhibition of NDM1 in Enterobacter cloacae isolate 4 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC after 24 hrs by broth microdilution assay (Rvb = 640 ug/ml) | Enterobacter cloacae | 3 | ALA4387701 | assay format | Scientific Literature | |
| 7. | ALA4387834 | B | Inhibition of NDM-7 in Escherichia coli isolate 2 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC after 24 hrs by broth microdilution assay (Rvb = 640 ug/ml) | Escherichia coli | 3 | ALA4387701 | assay format | Scientific Literature | |
| 8. | ALA4387835 | B | Inhibition of NDM4 in Escherichia coli isolate 3 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC after 24 hrs by broth microdilution assay (Rvb = 1280 ug/ml) | Escherichia coli | 3 | ALA4387701 | single protein format | Scientific Literature | |
| 9. | ALA4387836 | B | Inhibition of NDM1 in Escherichia coli isolate 1 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC after 24 hrs by broth microdilution assay (Rvb = 1280 ug/ml) | Escherichia coli | 3 | ALA4387701 | assay format | Scientific Literature | |
| 10. | ALA4387837 | B | Inhibition of IMP-4 in Escherichia coli ATCC 25922 assessed as potentiation of meropenem-induced antibacterial activity by measuring diameter of inhibition zone measured after 18 hrs by agar disk diffusion method | Escherichia coli ATCC 25922 | 2 | ALA4387701 | assay format | Scientific Literature | |
| 11. | ALA4387838 | B | Inhibition of NDM4 in Escherichia coli ATCC 25922 assessed as potentiation of meropenem-induced antibacterial activity by measuring diameter of inhibition zone measured after 18 hrs by agar disk diffusion method | Escherichia coli ATCC 25922 | 2 | ALA4387701 | single protein format | Scientific Literature | |
| 12. | ALA4387839 | B | Inhibition of IMP-4 in Escherichia coli ATCC 25922 assessed as potentiation of meropenem-induced antibacterial activity by measuring zone of inhibition by agar disk diffusion method (Rvb = 9.7 millimeter) | Escherichia coli ATCC 25922 | 3 | ALA4387701 | assay format | Scientific Literature | |
| 13. | ALA4387840 | B | Inhibition of NDM4 in Escherichia coli ATCC 25922 assessed as potentiation of meropenem-induced antibacterial activity by measuring zone of inhibition by agar disk diffusion method (Rvb = 9.8 millimeter) | Escherichia coli ATCC 25922 | 3 | ALA4387701 | single protein format | Scientific Literature | |
| 14. | ALA4387841 | B | Inhibition of NDM1 in Escherichia coli isolate 9 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC after 24 hrs by broth microdilution assay (Rvb = 320 ug/ml) | Escherichia coli | 3 | ALA4387701 | assay format | Scientific Literature | |
| 15. | ALA4387842 | B | Inhibition of IMP4 in Klebsiella pneumoniae isolate 10 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC after 24 hrs by broth microdilution method (Rvb = 64 ug/ml) | Klebsiella pneumoniae | 3 | ALA4387701 | assay format | Scientific Literature | |
| 16. | ALA4387843 | B | Inhibition of IMP4 in Escherichia coli isolate 11 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC after 24 hrs by broth microdilution method (Rvb = 32 ug/ml) | Escherichia coli | 3 | ALA4387701 | assay format | Scientific Literature | |
| 17. | ALA4387844 | B | Inhibition of IMP4 in Klebsiella pneumoniae isolate 12 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC after 24 hrs by broth microdilution method (Rvb = 16 ug/ml) | Klebsiella pneumoniae | 3 | ALA4387701 | assay format | Scientific Literature | |
| 18. | ALA4387845 | B | Inhibition of IMP4 in Klebsiella pneumoniae isolate 13 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC after 24 hrs by broth microdilution method (Rvb = 320 ug/ml) | Klebsiella pneumoniae | 3 | ALA4387701 | assay format | Scientific Literature | |
| 19. | ALA4387846 | B | Inhibition of IMP4 in Escherichia coli isolate 14 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC after 24 hrs by broth microdilution method (Rvb = 16 ug/ml) | Escherichia coli | 3 | ALA4387701 | assay format | Scientific Literature | |
| 20. | ALA4387847 | B | Inhibition of IMP4 in Enterobacter cloacae isolate 15 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC after 24 hrs by broth microdilution method (Rvb = 32 ug/ml) | Enterobacter cloacae | 3 | ALA4387701 | assay format | Scientific Literature |
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