# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4304840 | A | Cytotoxicity against ICR mouse peritoneal macrophages assessed as reduction in cell viability at 10 uM measured after 24 hrs by MTT assay | Mus musculus | 16 | ALA4304739 | cell-based format | Scientific Literature | |
2. | ALA4304841 | B | Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced IL-6 production at 10 uM preincubated for 2 hrs followed by LPS-stimulation and measured after 22 hrs by ELISA relative to control | Mus musculus | 17 | ALA4304739 | protein complex format | Scientific Literature | |
3. | ALA4304842 | B | Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced TNFalpha production at 10 uM preincubated for 2 hrs followed by LPS-stimulation and measured after 22 hrs by ELISA relative to control | Mus musculus | 15 | ALA4304739 | protein complex format | Scientific Literature | |
4. | ALA4304843 | B | Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced IL-6 production preincubated for 2 hrs followed by LPS-stimulation and measured after 22 hrs by ELISA | Mus musculus | 4 | ALA4304739 | protein complex format | Scientific Literature | |
5. | ALA4304844 | B | Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced TNFalpha production preincubated for 2 hrs followed by LPS-stimulation and measured after 22 hrs by ELISA | Mus musculus | 4 | ALA4304739 | protein complex format | Scientific Literature |