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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA4426199 B Agonist activity at human S1P1 receptor expressed in CHO cell membranes measured after 45 mins by [35S]GTP-gammaS binding assay Homo sapiens 28 ALA4425115 cell-based format Scientific Literature 2. ALA4426200 B Agonist activity at human S1P1 receptor expressed in CHO cell membranes measured after 45 mins by [35S]GTP-gammaS binding assay relative to control Homo sapiens 26 ALA4425115 cell-based format Scientific Literature 3. ALA4426201 A Agonist activity at human S1P3 receptor expressed in HEK293T cell co-expressing G-alpha15-BLA measured after 45 mins by [35S]GTP-gammaS binding assay Homo sapiens 28 ALA4425115 assay format Scientific Literature 4. ALA4426202 A Agonist activity at human S1P3 receptor expressed in HEK293T cell co-expressing G-alpha15-BLA measured after 45 mins by [35S]GTP-gammaS binding assay relative to control Homo sapiens 26 ALA4425115 assay format Scientific Literature 5. ALA4426203 B Selectivity ratio, ratio of EC50 for human S1P3 receptor expressed in HEK293T cell co-expressing G-alpha15-BLA to EC50 for human S1P1 receptor expressed in CHO cell membranes Homo sapiens 6 ALA4425115 cell-based format Scientific Literature 6. ALA4426210 B Agonist activity at S1P4 receptor (unknown origin) measured after 45 mins by [35S]GTP-gammaS binding assay Homo sapiens 4 ALA4425115 single protein format Scientific Literature 7. ALA4426218 B Agonist activity at S1P4 receptor (unknown origin) measured after 45 mins by [35S]GTP-gammaS binding assay relative to control Homo sapiens 4 ALA4425115 single protein format Scientific Literature 8. ALA4426219 B Agonist activity at S1P5 receptor (unknown origin) measured after 45 mins by [35S]GTP-gammaS binding assay Homo sapiens 4 ALA4425115 single protein format Scientific Literature 9. ALA4426220 B Agonist activity at S1P5 receptor (unknown origin) measured after 45 mins by [35S]GTP-gammaS binding assay relative to control Homo sapiens 4 ALA4425115 single protein format Scientific Literature 10. ALA4426221 F Reduction in blood lymphocytes in Lewis rat at 0.3 mg/kg, po measured after 24 hrs relative to control Rattus norvegicus 6 ALA4425115 organism-based format Scientific Literature 11. ALA4426223 A Cmax in mouse plasma at 1 mg/kg, iv or 1 mg/kg, po Mus musculus 2 ALA4425115 organism-based format Scientific Literature 12. ALA4426224 A Cmax in rat plasma at 2 mg/kg, iv or 5 mg/kg, po Rattus norvegicus 2 ALA4425115 organism-based format Scientific Literature 13. ALA4426225 A Cmax in cynomolgus monkey plasma at 1 mg/kg, iv or 1 mg/kg, po Macaca fascicularis 2 ALA4425115 organism-based format Scientific Literature 14. ALA4426227 A Tmax in mouse at 1 mg/kg, iv or 1 mg/kg, po Mus musculus 2 ALA4425115 organism-based format Scientific Literature 15. ALA4426228 A Tmax in rat at 2 mg/kg, iv or 5 mg/kg, po Rattus norvegicus 2 ALA4425115 organism-based format Scientific Literature 16. ALA4426229 A Tmax in cynomolgus monkey at 1 mg/kg, iv or 1 mg/kg, po Macaca fascicularis 2 ALA4425115 organism-based format Scientific Literature 17. ALA4426231 A AUC (0 to 24 hrs) in mouse at 1 mg/kg, iv or 1 mg/kg, po Mus musculus 2 ALA4425115 organism-based format Scientific Literature 18. ALA4426232 A AUC (0 to 24 hrs) in rat at 2 mg/kg, iv or 5 mg/kg, po Rattus norvegicus 2 ALA4425115 organism-based format Scientific Literature 19. ALA4426233 A AUC (0 to 24 hrs) in cynomolgus monkey at 1 mg/kg, iv or 1 mg/kg, po Macaca fascicularis 2 ALA4425115 organism-based format Scientific Literature 20. ALA4426235 A Clearance in mouse at 1 mg/kg, iv Mus musculus 2 ALA4425115 organism-based format Scientific Literature