| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4390139 | B | Inhibition of human endothelial lipase derived from human HT1080 cell conditioned media using PED-A1 as substrate incubated for 20 mins and measured every 20 secs for 10 mins by FRET assay | Homo sapiens | 11 | single protein format | Scientific Literature | ||
| 2. | ALA4390140 | B | Inhibition of human hepatic lipase expressed in African green monkey COS7 cells using PED-A1 as substrate incubated for 20 mins and measured every 20 secs for 10 mins by FRET assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 3. | ALA4390141 | B | Inhibition of mouse endothelial lipase expressed in HEK293F cells using D31-POPC-HDL as substrate incubated for 2 hrs in presence of mouse plasma by LC/MS analysis | Mus musculus | 8 | cell-based format | Scientific Literature | ||
| 4. | ALA4390148 | A | Permeability of compound at pH 5.5 by PAMPA | 6 | assay format | Scientific Literature | |||
| 5. | ALA4390149 | A | Permeability of compound at pH 7.4 by PAMPA | 5 | assay format | Scientific Literature | |||
| 6. | ALA4390150 | B | Selectivity index, ratio of IC50 for inhibition of human hepatic lipase expressed in African green monkey COS7 cells to IC50 for inhibition of human endothelial lipase derived from human HT1080 cell conditioned media | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 7. | ALA4390151 | B | Inhibition of human endothelial lipase using D31-POPC-HDL as substrate incubated for 2 hrs in presence of human serum by LC/MS analysis | Homo sapiens | 4 | single protein format | Scientific Literature |
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