# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4387398 | B | Competitive inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli assessed as reduction in urea production by measuring dissociation constant for enzyme-inhibitor complex using L-arginine as substrate by Berthelot colorimetric method based Dixon/Cornish-Bowden plot analysis relative to control | Leishmania amazonensis | 10 | ALA4385644 | assay format | Scientific Literature | |
2. | ALA4387399 | B | Inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli assessed as reduction in urea production using L-arginine as substrate by Berthelot colorimetric method relative to control | Leishmania amazonensis | 10 | ALA4385644 | assay format | Scientific Literature | |
3. | ALA4387400 | B | Inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli assessed as reduction in urea production at 100 uM using L-arginine as substrate by Berthelot colorimetric method relative to control | Leishmania amazonensis | 8 | ALA4385644 | assay format | Scientific Literature | |
4. | ALA4387401 | B | Mixed type inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli assessed as reduction in urea production by measuring dissociation constant for enzyme-substrate-inhibitor complex using L-arginine as substrate by Berthelot colorimetric method based Dixon/Cornish-Bowden plot analysis relative to control | Leishmania amazonensis | 10 | ALA4385644 | assay format | Scientific Literature | |
5. | ALA4387402 | F | Antileishmanial activity against Leishmania amazonensis MHOM/BR/1973/M2269 promastigotes assessed as inhibition of parasite growth incubated for 72 hrs by MTT assay | Leishmania amazonensis | 10 | ALA4385644 | organism-based format | Scientific Literature |