| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4333011 | B | Inhibition of recombinant full-length human C-terminal His6-tagged PARG (1 to 976 residues) expressed in Escherichia coli BL21 (DE3) cells using 6HIS-TEV-PARylated-PARP1 (2 to 1014 residues) as substrate measured after 10 mins by HTRF assay | Homo sapiens | 10 | ALA4330125 | cell-based format | Scientific Literature | |
| 2. | ALA4333012 | B | Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured after 30 to 120 mins by Alexafluor 488-conjugated secondary antibody and Hoechst 33342 staining based assay | Homo sapiens | 10 | ALA4330125 | cell-based format | Scientific Literature | |
| 3. | ALA4333013 | A | Half life in mouse liver microsomes | Mus musculus | 10 | ALA4330125 | microsome format | Scientific Literature | |
| 4. | ALA4333014 | A | Half life in human liver microsomes | Homo sapiens | 5 | ALA4330125 | microsome format | Scientific Literature |
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