| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4422592 | B | Inhibition of StrepTag-tagged human SARM1 TIR (561 to 724 residues) expressed in NRK1-HEK293T cells assessed as reduction in NADase activity by measuring NAD consumption at 150 uM pre-incubated up to 120 mins before NAD+ addition and further incubated for 60 mins by HPLC analysis relative to control | Homo sapiens | 6 | cell-based format | Patent Bioactivity Data | ||
| 2. | ALA4422593 | B | Inhibition of StrepTag-tagged human SARM1 TIR (561 to 724 residues) expressed in NRK1-HEK293T cells assessed as reduction in NADase activity by measuring ADPR production at 150 uM pre-incubated up to 120 mins before NAD+ addition and further incubated for 60 mins by HPLC analysis | Homo sapiens | 6 | cell-based format | Patent Bioactivity Data |
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