# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4390178 | Functional | Antibacterial activity against Bacillus subtilis ATCC 9372 incubated for 24 hrs by CLSI protocol based broth microdilution method | Bacillus subtilis | 48 | ALA4387753 | organism-based format | Scientific Literature | |
2. | ALA4390179 | Functional | Antibacterial activity against Bacillus pumilus CMCC63202 incubated for 24 hrs by CLSI protocol based broth microdilution method | Bacillus pumilus | 48 | ALA4387753 | organism-based format | Scientific Literature | |
3. | ALA4390180 | Functional | Antibacterial activity against Staphylococcus aureus ATCC 25923 incubated for 24 hrs by CLSI protocol based broth microdilution method | Staphylococcus aureus | 49 | ALA4387753 | organism-based format | Scientific Literature | |
4. | ALA4390181 | Functional | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 incubated for 24 hrs by CLSI protocol based broth microdilution method | Staphylococcus aureus | 49 | ALA4387753 | organism-based format | Scientific Literature | |
5. | ALA4390182 | Functional | Antibacterial activity against penicillin-resistant Staphylococcus aureus clinical isolate incubated for 24 hrs by CLSI protocol based broth microdilution method | Staphylococcus aureus | 49 | ALA4387753 | organism-based format | Scientific Literature | |
6. | ALA4390183 | Functional | Antibacterial activity against Staphylococcus aureus clinical isolate incubated for 24 hrs by CLSI protocol based broth microdilution method | Staphylococcus aureus | 33 | ALA4387753 | organism-based format | Scientific Literature | |
7. | ALA4390184 | Functional | Antibacterial activity against Escherichia coli ATCC 25922 incubated for 24 hrs by CLSI protocol based broth microdilution method | Escherichia coli | 48 | ALA4387753 | organism-based format | Scientific Literature | |
8. | ALA4390185 | Functional | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 incubated for 24 hrs by CLSI protocol based broth microdilution method | Pseudomonas aeruginosa | 48 | ALA4387753 | organism-based format | Scientific Literature | |
9. | ALA4390186 | Functional | Ratio of MBC for Staphylococcus aureus ATCC 25923 to MIC for Staphylococcus aureus ATCC 25923 | Staphylococcus aureus | 4 | ALA4387753 | organism-based format | Scientific Literature | |
10. | ALA4390187 | Functional | Ratio of MBC for methicillin-resistant Staphylococcus aureus ATCC 43300 to MIC for methicillin-resistant Staphylococcus aureus ATCC 43300 | Staphylococcus aureus | 4 | ALA4387753 | organism-based format | Scientific Literature | |
11. | ALA4390188 | Functional | Ratio of MBC for penicillin-resistant Staphylococcus aureus clinical isolate to MIC for penicillin-resistant Staphylococcus aureus clinical isolate | Staphylococcus aureus | 4 | ALA4387753 | organism-based format | Scientific Literature | |
12. | ALA4390189 | Functional | Bactericidal activity against methicillin-resistant Staphylococcus aureus ATCC 43300 assessed as log reduction in viable bacterial count at 1 to 8 times MIC incubated for 24 hrs by time-kill curve assay | Staphylococcus aureus | 1 | ALA4387753 | organism-based format | Scientific Literature | |
13. | ALA4390193 | Functional | Effect on bacterial cell morphology in Bacillus pumilus CMCC63202 assessed as increase in bacterial cell length at 0.5 times MIC incubated for 18 hrs by phase-contrast optical microscopic analysis | Bacillus pumilus | 1 | ALA4387753 | organism-based format | Scientific Literature | |
14. | ALA4390194 | Binding | Induction of Bacillus subtilis FtsZ polymerization in presence of GTP measured over 30 mins by microtiter plate-based light-scattering assay | Bacillus subtilis | 1 | ALA4387753 | single protein format | Scientific Literature | |
15. | ALA4390195 | ADME | Stability in mouse plasma assessed as degradation of compound at 25 ug/ml incubated for 24 hrs by RP-HPLC analysis | Mus musculus | 2 | ALA4387753 | cell-free format | Scientific Literature | |
16. | ALA4390196 | ADME | Half life in mouse plasma at 25 ug/ml incubated for 24 hrs by RP-HPLC analysis | Mus musculus | 1 | ALA4387753 | cell-free format | Scientific Literature | |
17. | ALA4390197 | ADME | Clearance in mouse liver microsomes incubated for 20 mins in presence of NADPH by RP-HPLC analysis | Mus musculus | 2 | ALA4387753 | microsome format | Scientific Literature | |
18. | ALA4390198 | ADME | Half life in mouse liver microsomes in presence of NADPH by RP-HPLC analysis | Mus musculus | 2 | ALA4387753 | microsome format | Scientific Literature | |
19. | ALA4390199 | ADME | Growth inhibition of human HeLa cells incubated for 48 hrs by MTT assay | Homo sapiens | 1 | ALA4387753 | cell-based format | Scientific Literature | |
20. | ALA4390200 | Functional | Bactericidal activity against Staphylococcus aureus ATCC 25923 assessed as 3 log reduction in number of colony forming units incubated for 24 hrs followed by aliquots transfer to tryptic soy agar and grown for 24 hrs | Staphylococcus aureus | 4 | ALA4387753 | organism-based format | Scientific Literature |