# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4395392 | B | Binding affinity to G-quadruplex G1 DNA (unknown origin) assessed as melting temperature at compound to DNA ratio of 4:1 in presence of 100 mM K+ by circular dichroism thermal denaturation analysis (Rvb= 52.6 degC) | Not specified | 14 | nucleic acid format | Scientific Literature | ||
2. | ALA4395393 | B | Binding affinity to G-quadruplex G1 DNA (unknown origin) assessed as melting temperature at compound to DNA ratio of 4:1 in presence of 150 mM Na+ by circular dichroism thermal denaturation analysis (Rvb = 57.4 degC) | Not specified | 14 | nucleic acid format | Scientific Literature | ||
3. | ALA4395394 | B | Binding affinity to human G-quadruplex G1 DNA assessed as equilibrium dissociation constant at 0.5 uM incubated for 30 mins under dark condition by fluorometric titration analysis | Homo sapiens | 7 | nucleic acid format | Scientific Literature | ||
4. | ALA4395396 | B | Binding affinity to 17 mer duplex D1 DNA (unknown origin) assessed as equilibrium dissociation constant at 0.5 uM incubated for 30 mins under dark condition by fluorometric titration analysis | Not specified | 7 | nucleic acid format | Scientific Literature | ||
5. | ALA4395397 | B | Ratio of Kd for human G-quadruplex G1 DNA to Kd for 17 mer duplex D1 DNA (unknown origin) by flourimetric titration analysis | 7 | assay format | Scientific Literature | |||
6. | ALA4395400 | B | Inhibition of telomerase activity in human HeLa cell lysate at 6.25 uM in presence of [32P]-labeled template primer by TRAP assay | Homo sapiens | 13 | subcellular format | Scientific Literature | ||
7. | ALA4395414 | B | Binding affinity to human G-quadruplex G1 DNA assessed as increase in fluorescence at 0.5 uM incubated for 30 mins in dark by fluorescence titration analysis relative to control | Homo sapiens | 7 | nucleic acid format | Scientific Literature |