#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4377464	A	Inhibition of recombinant human JAK1 kinase domain using 5FAM-KKSRGDYMTMQID as substrate incubated for 3 hrs by caliper method	Homo sapiens	1	ALA4376812	single protein format	Scientific Literature
2.	ALA4377465	A	Inhibition of recombinant human JAK2 kinase domain using FITC-KGGEEEEYFELVKK as substrate incubated for 60 mins by caliper method	Homo sapiens	1	ALA4376812	single protein format	Scientific Literature
3.	ALA4377466	A	Inhibition of recombinant human JAK3 kinase domain using FITC-KGGEEEEYFELVKK as substrate incubated for 75 mins by caliper method	Homo sapiens	1	ALA4376812	single protein format	Scientific Literature
4.	ALA4377467	B	Inhibition of recombinant human TYK2 JH1 kinase domain using 5FAM-KKSRGDYMTMQID as substrate incubated for 135 mins by caliper method	Homo sapiens	1	ALA4376812	single protein format	Scientific Literature
5.	ALA4675809	B	Inhibition of recombinant human His-tagged TYK2 expressed in baculovirus infected Sf21 cells using 5FAM-KKSRGDYMTMQID as substrate in presence of ATP at Km by microfluidic assay	Homo sapiens	21	ALA4673239	cell-based format	Scientific Literature
6.	ALA4675810	P	Octanol/water phosphate buffer partition coefficient, log D of compound at pH 7.4 by shake-flask method		21	ALA4673239	small-molecule physicochemical format	Scientific Literature
7.	ALA4675811	A	Apparent permeability in MDCK-II cells	Canis lupus familiaris	18	ALA4673239	cell-based format	Scientific Literature
8.	ALA4675812	A	Inhibition of recombinant human GST-tagged JAK1 catalytic domain (866 to 1154 residues) expressed in baculovirus expression system using 5FAM-KKSRGDYMTMQID as substrate in presence of ATP at Km by microfluidic assay	Homo sapiens	18	ALA4673239	assay format	Scientific Literature
9.	ALA4675813	A	Inhibition of recombinant human GST-tagged JAK2 catalytic domain (809 to 1153+9 residues) expressed in baculovirus expression system using FITC-KGGEEEEYFELVKK as substrate in presence of ATP at Km by microfluidic assay	Homo sapiens	18	ALA4673239	assay format	Scientific Literature
10.	ALA4675814	B	Inhibition of recombinant human GST-tagged JAK3 catalytic domain (781 to 1124 residues) expressed in baculovirus expression system using FITC-KGGEEEEYFELVKK as substrate in presence of ATP at Km by microfluidic assay	Homo sapiens	18	ALA4673239	assay format	Scientific Literature
11.	ALA4675815	A	Clearance in human liver microsomes assessed per mg protein	Homo sapiens	18	ALA4673239	microsome format	Scientific Literature
12.	ALA4675817	B	Selectivity ratio of IC50 for recombinant human GST-tagged JAK2 catalytic domain (809 to 1153+9 residues) expressed in baculovirus expression system to IC50 for inhibition of recombinant human His-tagged TYK2 expressed in baculovirus infected Sf21 cells	Homo sapiens	5	ALA4673239	cell-based format	Scientific Literature
13.	ALA4675818	A	Fraction unbound in human plasma	Homo sapiens	5	ALA4673239	cell-free format	Scientific Literature
14.	ALA4675819	B	Inhibition of JAK1/TYK2 signaling pathway in human whole blood assessed as reduction in IL-12 induced STAT4 phosphorylation preincubated for 45 mins followed by IL-12 addition and measured measured after 15 mins by immunostaining based FACS assay	Homo sapiens	5	ALA4673239	tissue-based format	Scientific Literature
15.	ALA4675820	A	Inhibition of JAK2 homodimer signaling pathway in human whole blood spiked with CD34 +ve cells assessed as reduction in EPO induced STAT5 phosphorylation preincubated for 45 mins followed by EPO addition and measured measured after 15 mins by immunostaining based FACS assay	Homo sapiens	5	ALA4673239	tissue-based format	Scientific Literature
16.	ALA4675821	U	Selectivity ratio of IC50 for inhibition of JAK2 homodimer signaling pathway in human whole blood spiked with CD34 +ve cells assessed as reduction in EPO induced STAT5 phosphorylation to IC80 for inhibition of JAK2 homodimer signaling pathway in human whole blood spiked with CD34 +ve cells assessed as reduction in EPO induced STAT5 phosphorylation	Homo sapiens	5	ALA4673239	assay format	Scientific Literature
17.	ALA4675822	A	Apparent clearance in human hepatocytes assessed per million cells	Homo sapiens	5	ALA4673239	cell-based format	Scientific Literature
18.	ALA4675823	P	Dissociation constant, basic pKa of compound		1	ALA4673239	small-molecule physicochemical format	Scientific Literature
19.	ALA4675824	P	Thermodynamic solubility of the compound at pH 7.4 using crystalline form of sample		1	ALA4673239	small-molecule physicochemical format	Scientific Literature
20.	ALA4675825	A	Substrate activity at MDR1 (unknown origin) assessed as efflux ratio	Homo sapiens	1	ALA4673239	single protein format	Scientific Literature