| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4395391 | B | Binding affinity to G-quadruplex G2 DNA (unknown origin) assessed as increase in deltaTm at compound to DNA ratio of 10:1 by fluorescence thermal denaturation analysis | Not specified | 10 | nucleic acid format | Scientific Literature | ||
| 2. | ALA4395392 | B | Binding affinity to G-quadruplex G1 DNA (unknown origin) assessed as melting temperature at compound to DNA ratio of 4:1 in presence of 100 mM K+ by circular dichroism thermal denaturation analysis (Rvb= 52.6 degC) | Not specified | 14 | nucleic acid format | Scientific Literature | ||
| 3. | ALA4395393 | B | Binding affinity to G-quadruplex G1 DNA (unknown origin) assessed as melting temperature at compound to DNA ratio of 4:1 in presence of 150 mM Na+ by circular dichroism thermal denaturation analysis (Rvb = 57.4 degC) | Not specified | 14 | nucleic acid format | Scientific Literature | ||
| 4. | ALA4395394 | B | Binding affinity to human G-quadruplex G1 DNA assessed as equilibrium dissociation constant at 0.5 uM incubated for 30 mins under dark condition by fluorometric titration analysis | Homo sapiens | 7 | nucleic acid format | Scientific Literature | ||
| 5. | ALA4395396 | B | Binding affinity to 17 mer duplex D1 DNA (unknown origin) assessed as equilibrium dissociation constant at 0.5 uM incubated for 30 mins under dark condition by fluorometric titration analysis | Not specified | 7 | nucleic acid format | Scientific Literature | ||
| 6. | ALA4395397 | B | Ratio of Kd for human G-quadruplex G1 DNA to Kd for 17 mer duplex D1 DNA (unknown origin) by flourimetric titration analysis | 7 | assay format | Scientific Literature | |||
| 7. | ALA4395400 | B | Inhibition of telomerase activity in human HeLa cell lysate at 6.25 uM in presence of [32P]-labeled template primer by TRAP assay | Homo sapiens | 13 | subcellular format | Scientific Literature | ||
| 8. | ALA4395401 | B | Inhibition of DNA polymerase activity in human HeLa cell lysate at 6.25 uM in presence of [32P]-labeled template primer by TRAP assay | Homo sapiens | 12 | subcellular format | Scientific Literature | ||
| 9. | ALA4395406 | B | Inhibition of telomerase activity in human HeLa cell lysate in presence of [32P]-labeled template primer by TRAP assay | Homo sapiens | 2 | subcellular format | Scientific Literature | ||
| 10. | ALA4395414 | B | Binding affinity to human G-quadruplex G1 DNA assessed as increase in fluorescence at 0.5 uM incubated for 30 mins in dark by fluorescence titration analysis relative to control | Homo sapiens | 7 | nucleic acid format | Scientific Literature | ||
| 11. | ALA4395416 | B | Inhibition of DNA polymerase activity in human HeLa cell lysate at 0.625 to 10 uM in presence of [32P]-labeled template primer by TRAP assay | Homo sapiens | 2 | subcellular format | Scientific Literature |
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