| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4401912 | B | Transactivation of GAL4-fused mouse RARalpha-LBD expressed in COS-7 cells after 24 hrs by bright-Glo reagent based assay | Mus musculus | 20 | cell-based format | Scientific Literature | ||
| 2. | ALA4401913 | B | Transactivation of GAL4-fused mouse RARbeta-LBD expressed in COS-7 cells after 24 hrs by bright-Glo reagent based assay | Mus musculus | 20 | cell-based format | Scientific Literature | ||
| 3. | ALA4401914 | B | Selectivity ratio of EC50 for GAL4-fused mouse RARalpha LBD expressed in COS-7 cells to EC50 for GAL4-fused mouse RARbeta-LBD expressed in COS-7 cells | Mus musculus | 20 | cell-based format | Scientific Literature | ||
| 4. | ALA4401915 | B | Transactivation of GAL4-fused mouse RARgamma-LBD expressed in COS-7 cells after 24 hrs by bright-Glo reagent based assay | Mus musculus | 20 | cell-based format | Scientific Literature | ||
| 5. | ALA4401916 | B | Selectivity ratio of EC50 for GAL4-fused mouse RARgamma-LBD expressed in COS-7 cells to EC50 for GAL4-fused mouse RARbeta-LBD expressed in COS-7 cells | Mus musculus | 19 | cell-based format | Scientific Literature | ||
| 6. | ALA4401917 | P | Octanol/buffer partition coefficient, log D of the compound at pH 7.4 by shake flask method | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 7. | ALA4401919 | A | Apparent permeability in MDCK-MDR1 cells | Canis lupus familiaris | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4401920 | A | Efflux ratio of apparent permeability in MDCK-MDR1 cells | Canis lupus familiaris | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4401921 | A | Inhibition of CYP1A2 in human liver microsomes by LC-MS/MS analysis | Homo sapiens | 1 | microsome format | Scientific Literature | ||
| 10. | ALA4401922 | A | Inhibition of CYP2C9 in human liver microsomes by LC-MS/MS analysis | Homo sapiens | 1 | microsome format | Scientific Literature | ||
| 11. | ALA4401923 | A | Inhibition of CYP2C19 in human liver microsomes by LC-MS/MS analysis | Homo sapiens | 1 | microsome format | Scientific Literature | ||
| 12. | ALA4401924 | A | Inhibition of CYP2D6 in human liver microsomes by LC-MS/MS analysis | Homo sapiens | 1 | microsome format | Scientific Literature | ||
| 13. | ALA4401925 | A | Inhibition of CYP3A4 in human liver microsomes by LC-MS/MS analysis | Homo sapiens | 1 | microsome format | Scientific Literature | ||
| 14. | ALA4401926 | A | Intrinsic clearance in human microsomes assessed per mg protein after 45 mins in presence of NADPH | Homo sapiens | 1 | microsome format | Scientific Literature | ||
| 15. | ALA4401927 | A | Clearance in Sprague-Dawley rat at 0.5 mg/kg, iv or 1 to 10 mg/kg, po by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA4401928 | A | Volume of distribution at steady state in Sprague-Dawley rat at 0.5 mg/kg, iv or 1 to 10 mg/kg, po by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA4401929 | A | Half life in Sprague-Dawley rat at 0.5 mg/kg, iv or 1 to 10 mg/kg, po by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA4401930 | A | Tmax in Sprague-Dawley rat at 0.5 mg/kg, iv or 1 to 10 mg/kg, po by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA4401931 | A | Fraction absorbed in Sprague-Dawley rat at 1 to 10 mg/kg, po by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA4401932 | A | Clearance in Beagle dog at 0.5 mg/kg, iv or 3 mg/kg, po by LC-MS/MS analysis | Canis lupus familiaris | 1 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!