# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4423789 | B | Inhibition of Toxoplasma gondii DHFR-TS expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed by substrate and NADPH addition and measured after 60 mins by resazurin dye based diaphorase-coupled assay | Toxoplasma gondii | 31 | ALA4422638 | cell-based format | Scientific Literature | |
2. | ALA4423790 | A | Inhibition of human DHFR expressed in Escherichia coli BL21 competent cells using DHF as substrate preincubated for 15 mins followed by substrate and NADPH addition and measured after 60 mins by resazurin dye based diaphorase-coupled assay | Homo sapiens | 31 | ALA4422638 | cell-based format | Scientific Literature | |
3. | ALA4423791 | T | Selectivity ratio of IC50 for human DHFR to IC50 for Toxoplasma gondii DHFR-TS | 29 | ALA4422638 | assay format | Scientific Literature |