# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4376261 | B | Inhibition of Pseudomonas aeruginosa tRNA (guanine(37)-N1)-methyltransferase (Leu5 to Asp25 residues) expressed in Escherichia coli BL21 (DE3) Rosetta T1R cells assessed as reduction in S-adenosyl-L-homocysteine production preincubated for 15 mins followed by 1.5 uM of tRNALeu(CAG) substrate and SAM addition and measured after 45 mins by MTase-Glo assay | Pseudomonas aeruginosa | 26 | cell-based format | Scientific Literature | ||
2. | ALA4376283 | F | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 at 100 uM incubated for 24 hrs | Staphylococcus aureus | 25 | organism-based format | Scientific Literature | ||
3. | ALA4376284 | F | Antibacterial activity against Enterococcus faecalis ATCC 51299 at 100 uM incubated for 24 hrs | Enterococcus faecalis | 25 | organism-based format | Scientific Literature | ||
4. | ALA4376285 | F | Antibacterial activity against Streptococcus pneumoniae ATCC 49619 at 100 uM incubated for 24 hrs | Streptococcus pneumoniae | 25 | organism-based format | Scientific Literature | ||
5. | ALA4376286 | F | Antibacterial activity against Mycolicibacterium smegmatis MC2 155 at 100 uM incubated for 24 hrs | Mycolicibacterium smegmatis | 25 | organism-based format | Scientific Literature | ||
6. | ALA4376287 | F | Antibacterial activity against Mycobacterium tuberculosis ATCC 27294 at 100 uM incubated for 7 days | Mycobacterium tuberculosis | 25 | organism-based format | Scientific Literature |