# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4331198 | B | Inhibition of recombinant human GST-tagged LRRK2 G2019S mutant catalytic domain (970 to 2527 residues) expressed in insect cells using RtGWWRFYTLRRARQGNTKQR as substrate measured after 180 mins in presence of [gamma33P]ATP by topcount method | Homo sapiens | 16 | ALA4330074 | cell-based format | Scientific Literature | |
2. | ALA4331199 | B | Inhibition of LRRK2 G2019S mutant (unknown origin) by cell based assay | Homo sapiens | 16 | ALA4330074 | cell-based format | Scientific Literature | |
3. | ALA4331200 | A | Efflux ratio of permeability from basolateral to apical side over apical to basolateral side in MDCK-MDR1 cells harboring human P-gp at 5 uM | Canis lupus familiaris | 16 | ALA4330074 | cell-based format | Scientific Literature | |
4. | ALA4331201 | A | Clearance in rat at 0.5 to 1 mg/kg, iv | Rattus norvegicus | 4 | ALA4330074 | organism-based format | Scientific Literature | |
5. | ALA4331202 | B | Selectivity ratio of Ki for JAK2 (unknown origin) to Ki for recombinant human GST-tagged LRRK2 G2019S mutant catalytic domain (970 to 2527 residues) expressed in insect cells | Homo sapiens | 4 | ALA4330074 | cell-based format | Scientific Literature | |
6. | ALA4331203 | B | Inhibition of MELK (unknown origin) at 1 uM relative to control | Homo sapiens | 1 | ALA4330074 | single protein format | Scientific Literature | |
7. | ALA4331204 | B | Inhibition of TTK (unknown origin) at 1 uM relative to control | Homo sapiens | 2 | ALA4330074 | single protein format | Scientific Literature | |
8. | ALA4331900 | B | Inhibition of recombinant human GST-tagged LRRK2 G2019S mutant catalytic domain (970 to 2527 residues) expressed in baculovirus expression system by radiometric assay | Homo sapiens | 37 | ALA4330096 | assay format | Scientific Literature | |
9. | ALA4331901 | A | Stability in human liver microsomes assessed as compound turnover rate measured after 40 mins | Homo sapiens | 17 | ALA4330096 | microsome format | Scientific Literature | |
10. | ALA4331902 | A | Stability in mouse liver microsomes assessed as compound turnover rate measured after 30 mins | Mus musculus | 17 | ALA4330096 | microsome format | Scientific Literature | |
11. | ALA4331964 | B | Inhibition of AMPK (unknown origin) at 1 uM relative to control | Homo sapiens | 2 | ALA4330096 | protein complex format | Scientific Literature | |
12. | ALA4331965 | B | Inhibition of Aurora B (unknown origin) at 1 uM relative to control | Homo sapiens | 2 | ALA4330096 | single protein format | Scientific Literature | |
13. | ALA4331966 | B | Inhibition of BRSK2 (unknown origin) at 1 uM relative to control | Homo sapiens | 2 | ALA4330096 | single protein format | Scientific Literature | |
14. | ALA4331967 | B | Inhibition of BTK (unknown origin) at 1 uM relative to control | Homo sapiens | 2 | ALA4330096 | single protein format | Scientific Literature | |
15. | ALA4331968 | B | Inhibition of CAMK1 (unknown origin) at 1 uM relative to control | Homo sapiens | 2 | ALA4330096 | single protein format | Scientific Literature | |
16. | ALA4331969 | B | Inhibition of CAMKKb (unknown origin) at 1 uM relative to control | Homo sapiens | 2 | ALA4330096 | single protein format | Scientific Literature | |
17. | ALA4331970 | B | Inhibition of CDK2/cyclinA (unknown origin) at 1 uM relative to control | Homo sapiens | 2 | ALA4330096 | protein complex format | Scientific Literature | |
18. | ALA4331971 | B | Inhibition of CHK1 (unknown origin) at 1 uM relative to control | Homo sapiens | 2 | ALA4330096 | single protein format | Scientific Literature | |
19. | ALA4331972 | B | Inhibition of CHK2 (unknown origin) at 1 uM relative to control | Homo sapiens | 2 | ALA4330096 | single protein format | Scientific Literature | |
20. | ALA4331973 | B | Inhibition of CK1 (unknown origin) at 1 uM relative to control | Homo sapiens | 2 | ALA4330096 | protein format | Scientific Literature |