# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4328666 | B | Inhibition of human GST-tagged catalytic ROCK1 expressed in baculovirus system using STK S2 peptide substrate and and 33P-ATP after 60 mins by HTRF assay | Homo sapiens | 44 | ALA4325872 | assay format | Scientific Literature | |
2. | ALA4328667 | B | Inhibition of GST-fused human recombinant ROCK2 (11 to 552 residues) expressed in Spodoptera frugiperda insect cells using STK S2 peptide substrate and 33P-ATP after 60 mins by HTRF assay | Homo sapiens | 45 | ALA4325872 | cell-based format | Scientific Literature | |
3. | ALA4328668 | B | Inhibition of PKA (unknown origin) | Homo sapiens | 43 | ALA4325872 | assay format | Scientific Literature | |
4. | ALA4328670 | P | Solubility of compound by high throughput assay | 13 | ALA4325872 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA4328671 | A | Protein binding in plasma (unknown origin) assessed as unbound fraction | Not specified | 14 | ALA4325872 | cell-free format | Scientific Literature | |
6. | ALA4328672 | A | Permeability of compound by PAMPA | 16 | ALA4325872 | assay format | Scientific Literature | ||
7. | ALA4328673 | A | Inhibition of C-terminal 4His-tagged CYP2C9 (unknown origin) expressed in Escherichia coli by spectrophotometric analysis | Homo sapiens | 11 | ALA4325872 | assay format | Scientific Literature | |
8. | ALA4328674 | A | Inhibition of C-terminal 4His-tagged CYP2D6 (unknown origin) expressed in Escherichia coli by spectrophotometric analysis | Homo sapiens | 10 | ALA4325872 | assay format | Scientific Literature | |
9. | ALA4328675 | A | Inhibition of C-terminal 4His-tagged CYP3A4 (unknown origin) expressed in Escherichia coli by spectrophotometric analysis | Homo sapiens | 11 | ALA4325872 | assay format | Scientific Literature | |
10. | ALA4328676 | B | Inhibition of ROCK1/2 in human PANC1 cells assessed as reduction in MYPT1 phosphorylation after 1 hr by ELISA | Homo sapiens | 14 | ALA4325872 | cell-based format | Scientific Literature |