| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4361683 | B | Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membrane | Rattus norvegicus | 17 | cell membrane format | Scientific Literature | ||
| 2. | ALA4361684 | B | Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membrane | Rattus norvegicus | 17 | cell membrane format | Scientific Literature | ||
| 3. | ALA4361685 | B | Selectivity index, ratio of Ki for alpha7 nAChR in rat hippocampus membrane to Ki for alpha4beta2 nAChR in rat cerebral cortex membrane | Rattus norvegicus | 16 | cell membrane format | Scientific Literature | ||
| 4. | ALA4361686 | B | Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membrane | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 5. | ALA4361687 | B | Selectivity index, ratio of Ki for human alpha3beta4 nAChR in HEK243 cell membrane to Ki for alpha4beta2 nAChR in rat cerebral cortex membrane | 16 | cell-based format | Scientific Literature | |||
| 6. | ALA4361688 | B | Agonist activity at human alpha4beta2 nAChR expressed in GH4C1 cells assessed as increase in inward channel current measured after 3 to 4 days at -70 mV holding potential by patch clamp assay relative to acetylcholine | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA4361689 | B | Agonist activity at human alpha4beta2 nAChR expressed in GH4C1 cells assessed as increase in inward channel current measured after 3 to 4 days at -70 mV holding potential by patch clamp assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA4361690 | B | Agonist activity at human alpha3beta4 nAChR expressed in GH4C1 cells assessed as increase in inward channel current at >1 uM measured after 3 to 4 days at -70 mV holding potential by patch clamp assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA4361691 | B | Agonist activity at human alpha3beta4 nAChR expressed in GH4C1 cells assessed as increase in inward channel current measured after 3 to 4 days at -70 mV holding potential by patch clamp assay | Homo sapiens | 2 | cell-based format | Scientific Literature |
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