| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4350283 | B | Inhibition of N-terminal GST tagged human recombinant EHMT1 (794 to 1294 residues) expressed in baculovirus infected Sf9 insect cells assessed as reduction in conversion of SAH to AMP using histone H3 as substrate and SAH as cosubstrate incubated for 30 mins by AMP Glo detection assay | Homo sapiens | 59 | ALA4346750 | cell-based format | Scientific Literature | |
| 2. | ALA4350284 | B | Inhibition of N-terminal GST tagged human recombinant EHMT2 (785 to 1210 residues) expressed in baculovirus infected Sf9 insect cells assessed as reduction in conversion of SAH to AMP using histone H3 as substrate and SAH as cosubstrate incubated for 30 mins by AMP Glo detection assay | Homo sapiens | 59 | ALA4346750 | cell-based format | Scientific Literature | |
| 3. | ALA4350285 | B | Selectivity ratio of IC50 for N-terminal GST tagged human recombinant EHMT2 (785 to 1210 residues) expressed in baculovirus infected Sf9 insect cells to IC50 for N-terminal GST tagged human recombinant EHMT1 (794 to 1294 residues) expressed in baculovirus infected Sf9 insect cells by peptide-based AlphaLISA | Homo sapiens | 46 | ALA4346750 | cell-based format | Scientific Literature | |
| 4. | ALA4350286 | B | Inhibition of EHMT1/2 in human AsPC1 cells assessed as H3K9Me2 level at 10 uM incubated for 48 hrs by Western blot analysis relative to control | Homo sapiens | 5 | ALA4346750 | cell-based format | Scientific Literature |
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