# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4341184 | F | Induction of autophagy in human Bel7402/5-FU cells assessed as increase in red fluorescence incubated for 72 hrs by acridine orange staining based fluorescence microscopy | Homo sapiens | 1 | ALA4340522 | cell-based format | Scientific Literature | |
2. | ALA4341185 | B | Inhibition of HDAC1 (unknown origin) using Boc-Lys (Ac)-AMC as substrate incubated for 60 mins and measured after 30 mins by fluorescence assay | Homo sapiens | 18 | ALA4340522 | single protein format | Scientific Literature | |
3. | ALA4341186 | F | Antiproliferative activity against human SMMC7721 cells incubated for 48 hrs by MTT assay | Homo sapiens | 18 | ALA4340522 | cell-based format | Scientific Literature | |
4. | ALA4341187 | F | Antiproliferative activity against human HepG2 cells incubated for 48 hrs by MTT assay | Homo sapiens | 18 | ALA4340522 | cell-based format | Scientific Literature | |
5. | ALA4341188 | F | Antiproliferative activity against human HCT116 cells incubated for 48 hrs by MTT assay | Homo sapiens | 18 | ALA4340522 | cell-based format | Scientific Literature | |
6. | ALA4341189 | F | Antiproliferative activity against human H1299 cells incubated for 48 hrs by MTT assay | Homo sapiens | 18 | ALA4340522 | cell-based format | Scientific Literature | |
7. | ALA4341190 | B | Potency index, ratio of SAHA IC50 to compound IC50 for inhibition of HDAC1 (unknown origin) using Boc-Lys (Ac)-AMC as substrate incubated for 60 mins and measured after 30 mins by fluorescence assay | Homo sapiens | 1 | ALA4340522 | single protein format | Scientific Literature | |
8. | ALA4341191 | A | Cytotoxicity against human LO2 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay | Homo sapiens | 1 | ALA4340522 | cell-based format | Scientific Literature | |
9. | ALA4341192 | T | Selectivity index, ratio of IC50 for human LO2 cells to IC50 for human HepG2 cells | Homo sapiens | 1 | ALA4340522 | assay format | Scientific Literature | |
10. | ALA4341193 | F | Antiproliferative activity against human Bel7402 cells incubated for 48 hrs by MTT assay | Homo sapiens | 9 | ALA4340522 | cell-based format | Scientific Literature | |
11. | ALA4341194 | F | Antiproliferative activity against human Bel7402/5-FU cells incubated for 48 hrs by MTT assay | Homo sapiens | 9 | ALA4340522 | cell-based format | Scientific Literature | |
12. | ALA4341195 | F | Potency index, ratio of SAHA IC50 to compound IC50 for antiproliferative activity against human Bel7402 cells incubated for 48 hrs by MTT assay | Homo sapiens | 1 | ALA4340522 | cell-based format | Scientific Literature | |
13. | ALA4341196 | F | Potency index, ratio of SAHA IC50 to compound IC50 for antiproliferative activity against human Bel7402/5-FU cells incubated for 48 hrs by MTT assay | Homo sapiens | 1 | ALA4340522 | cell-based format | Scientific Literature | |
14. | ALA4341197 | F | Potency index, ratio of 5-FU IC50 to compound IC50 for antiproliferative activity against human Bel7402 cells incubated for 48 hrs by MTT assay | Homo sapiens | 1 | ALA4340522 | cell-based format | Scientific Literature | |
15. | ALA4341198 | F | Potency index, ratio of 5-FU IC50 to compound IC50 for antiproliferative activity against human Bel7402/5-FU cells incubated for 48 hrs by MTT assay | Homo sapiens | 1 | ALA4340522 | cell-based format | Scientific Literature | |
16. | ALA4341199 | B | Inhibition of human recombinant HDAC3 using Boc-Lys (Ac)-AMC as substrate incubated for 60 mins and measured after 30 mins by fluorescence assay | Homo sapiens | 5 | ALA4340522 | single protein format | Scientific Literature | |
17. | ALA4341200 | B | Inhibition of human recombinant HDAC6 using Boc-Lys (Ac)-AMC as substrate incubated for 60 mins and measured after 30 mins by fluorescence assay | Homo sapiens | 5 | ALA4340522 | single protein format | Scientific Literature | |
18. | ALA4341201 | B | Inhibition of human recombinant HDAC8 using Boc-Lys (Ac)-AMC as substrate incubated for 60 mins and measured after 30 mins by fluorescence assay | Homo sapiens | 5 | ALA4340522 | single protein format | Scientific Literature | |
19. | ALA4341202 | B | Inhibition of human HDAC1 in Bel7402/5-FU cells assessed as up regulation of Ac-H3 protein at 0.8 uM incubated for 72 hrs by Western blotting assay | Homo sapiens | 1 | ALA4340522 | cell-based format | Scientific Literature | |
20. | ALA4341203 | B | Inhibition of HDAC1 in human Bel7402/5-FU cells assessed as up regulation of Ac-H3 expression at 0.8 to 5.0 uM incubated for 72 hrs by Western blot assay | Homo sapiens | 1 | ALA4340522 | cell-based format | Scientific Literature |